M
M. Jensen
Researcher at University of North Carolina at Chapel Hill
Publications - 7
Citations - 1345
M. Jensen is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Transcription factor & Regulation of gene expression. The author has an hindex of 4, co-authored 6 publications receiving 1250 citations.
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Journal ArticleDOI
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
Mark Gerstein,Zhi John Lu,Eric L. Van Nostrand,Chao Cheng,Bradley I. Arshinoff,Tao Liu,Kevin Y. Yip,R. Robilotto,Andreas Rechtsteiner,Kohta Ikegami,P. Alves,A. Chateigner,Marc D. Perry,Mitzi Morris,Raymond K. Auerbach,X. Feng,Jing Leng,A. Vielle,Wei Niu,Kahn Rhrissorrakrai,Ashish Agarwal,Roger P. Alexander,Galt P. Barber,Cathleen M. Brdlik,J. Brennan,Jeremy Brouillet,Adrian Carr,Ming Sin Cheung,Hiram Clawson,Sergio Contrino,Luke Dannenberg,Abby F. Dernburg,Arshad Desai,L. Dick,Andréa C. Dosé,Jiang Du,Thea A. Egelhofer,Sevinc Ercan,Ghia Euskirchen,Brent Ewing,Elise A. Feingold,Reto Gassmann,Peter J. Good,Philip Green,Francois Gullier,M. Gutwein,Mark S. Guyer,Lukas Habegger,Ting Han,Jorja G. Henikoff,Stefan R. Henz,Angie S. Hinrichs,H. Holster,Tony Hyman,A. Leo Iniguez,J. Janette,M. Jensen,Masaomi Kato,W. James Kent,E. Kephart,Vishal Khivansara,Ekta Khurana,John Kim,P. Kolasinska-Zwierz,Eric C. Lai,Isabel J. Latorre,Amber Leahey,Suzanna E. Lewis,Paul Lloyd,Lucas Lochovsky,Rebecca F. Lowdon,Yaniv Lubling,Rachel Lyne,Michael J. MacCoss,Sebastian D. Mackowiak,Marco Mangone,Sheldon J. McKay,D. Mecenas,Gennifer E. Merrihew,David M. Miller,A. Muroyama,John I. Murray,Siew Loon Ooi,Hoang Pham,T. Phippen,Elicia Preston,Nikolaus Rajewsky,Gunnar Rätsch,Heidi Rosenbaum,Joel Rozowsky,Kim Rutherford,P. Ruzanov,Mihail Sarov,Rajkumar Sasidharan,Andrea Sboner,P. Scheid,Eran Segal,Hyunjin Shin,C. Shou,Frank J. Slack,C. Slightam,Richard J.H. Smith,William C. Spencer,Eo Stinson,S. Taing,Teruaki Takasaki,D. Vafeados,Ksenia Voronina,Guilin Wang,Nicole L. Washington,Christina M. Whittle,Beijing Wu,Koon-Kiu Yan,Georg Zeller,Z. Zha,Mei Zhong,Xingliang Zhou,Julie Ahringer,Susan Strome,Kristin C. Gunsalus,Gos Micklem,X. Shirley Liu,Valerie Reinke,Stuart K. Kim,LaDeana W. Hillier,Steven Henikoff,Fabio Piano,Michael Snyder,Lincoln Stein,Jason D. Lieb,Robert H. Waterston +130 more
TL;DR: These studies identified regions of the nematode and fly genomes that show highly occupied targets (or HOT) regions where DNA was bound by more than 15 of the transcription factors analyzed and the expression of related genes were characterized, providing insights into the organization, structure, and function of the two genomes.
Journal ArticleDOI
Broad chromosomal domains of histone modification patterns in C. elegans
Tao Liu,Andreas Rechtsteiner,Thea A. Egelhofer,A. Vielle,Isabel J. Latorre,Ming Sin Cheung,Sevinc Ercan,Kohta Ikegami,M. Jensen,P. Kolasinska-Zwierz,Heidi Rosenbaum,Hyunjin Shin,S. Taing,Teruaki Takasaki,A. Leonardo Iniguez,Arshad Desai,Abby F. Dernburg,Hiroshi Kimura,Jason D. Lieb,Julie Ahringer,Susan Strome,X. Shirley Liu +21 more
TL;DR: The genome-wide distributions of 19 histone modifications, one histone variant, and eight chromatin-associated proteins in Caenorhabditis elegans embryos and L3 larvae are defined, allowing for in-depth analysis of the organization and deployment of the C. elegans genome during development.
Journal ArticleDOI
The ZFP-1(AF10)/DOT-1 Complex Opposes H2B Ubiquitination to Reduce Pol II Transcription
TL;DR: ZFP-1 and its interacting partner DOT-1.1 have a global role in negatively modulating the level of polymerase II (Pol II) transcription on essential widely expressed genes and contribute to progressive Pol II pausing on essential genes during development and to rapid Pol IIPausing during stress response.
Journal ArticleDOI
A Conserved PHD Finger Protein and Endogenous RNAi Modulate Insulin Signaling in Caenorhabditis elegans
Andres R. Mansisidor,Germano Cecere,Sebastian Hoersch,Sebastian Hoersch,M. Jensen,Trupti Kawli,Lisa M. Kennedy,Violeta Chavez,Man-Wah Tan,Jason D. Lieb,Alla Grishok +10 more
TL;DR: It is demonstrated that overexpression of ZFP-1 caused an increased resistance to oxidative stress in a DAF-16–dependent manner, suggesting that epigenetic regulation of key upstream signaling components in signal transduction pathways through chromatin and RNAi may have a large impact on the outcome of signaling
Identification of Transcription Factor LIN-15B::GFP Binding Regions in L3
Mb Gerstein,Zj Lu,El Van Nostrand,Chao Cheng,Bi Arshinoff,Tao Liu,Ky Yip,R. Robilotto,Andreas Rechtsteiner,Kohta Ikegami,P. Alves,A. Chateigner,Marc D. Perry,M. Morris,Rk Auerbach,X. Feng,Jing Leng,A. Vielle,Wei Niu,Kahn Rhrissorrakrai,Ashish Agarwal,Rp Alexander,Galt P. Barber,Cm Brdlik,J. Brennan,Jj Brouillet,Adrian Carr,Cheung,Hiram Clawson,Sergio Contrino,Lo Dannenberg,Af Dernburg,Arshad Desai,L. Dick,Ac Dose,Jiang Du,Thea A. Egelhofer,Sevinc Ercan,Ghia Euskirchen,Brent Ewing,Ea Feingold,Reto Gassmann,Pj Good,Philip Green,F. Gullier,M. Gutwein,Guyer,Lukas Habegger,Ting Han,Jg Henikoff,Henz,Angie S. Hinrichs,H. Holster,Tony Hyman,Al Iniguez,J. Janette,M. Jensen,Masaomi Kato,Wj Kent,E. Kephart,Khivansara,Ekta Khurana,Jk Kim,P. Kolasinska-Zwierz,Ec Lai,Isabel J. Latorre,A. Leahey,Suzanna E. Lewis,Paul Lloyd,Lucas Lochovsky,Rf Lowdon,Yaniv Lubling,Rachel Lyne,Michael J. MacCoss,Sd Mackowiak,Marco Mangone,Sheldon J. McKay,D. Mecenas,Gennifer E. Merrihew,Dm Miller,A. Muroyama,Ji Murray,Sl Ooi,H. Pham,T. Phippen,Ea Preston,Nikolaus Rajewsky,Gunnar Rätsch,Heidi Rosenbaum,Joel Rozowsky,Kim Rutherford,P. Ruzanov,Mihail Sarov,Rajkumar Sasidharan,Andrea Sboner,P. Scheid,Eran Segal,Hyunjin Shin,C. Shou,Fj Slack,C. Slightam,Richard J.H. Smith,Wc Spencer,Eo Stinson,S. Taing,Teruaki Takasaki,D. Vafeados,K. Voronina,Guilin Wang,Nl Washington,Cm Whittle,Beijing Wu,Kk Yan,Georg Zeller,Z. Zha,Mei Zhong,X. Zhou,Julie Ahringer,Susan Strome,Kc Gunsalus,Gos Micklem,Xs Liu,Reinke,Sk Kim,Lw Hillier,Steven Henikoff,Fabio Piano,Michael Snyder,Lincoln Stein,Lieb,Rh Waterston,C. Chen,Elicia Preston,C. Slightham,L. Jiang,Aa Hyman,Mark Gerstein +136 more