Giancarlo Forte

TL;DR: A critical review of the recent insights into the molecular basis of cellular mechanotransduction is provided, by analyzing how mechanical stimuli get transformed into a given biological response through the activation of a peculiar genetic program.

TL;DR: The molecular mechanism by which cell spreading and RhoA GTPase activity control FA formation through YAP to stabilize the anchorage of the actin cytoskeleton to the cell membrane is unveiled and qualified as the key determinant of cell mechanics in response to ECM cues.

TL;DR: It is shown that short‐term exposure of mesenchymal stem cells to HGF can induce the activation of its cognate Met receptor and the downstream effectors ERK1/2, p38MAPK, and PI3K/Akt, while long-term exposure to H GF resulted in cytoskeletal rearrangement, cell migration, and marked inhibition of proliferation through the arrest in the G1‐S checkpoint.

TL;DR: It is reported that 24 h exposure to 5, 10, and 50 μg/mL of nanoceria did not affect cell growth and function in cardiac progenitor cells, while being able to protect CPCs from H(2)O(2)-induced cytotoxicity for at least 7 days, indicating that Nanoceria in an effective antioxidant.

TL;DR: A novel (scalable) electrospinning process was developed to fabricate bio-inspired multiscale three-dimensional scaffolds endowed with a controlled multimodal distribution of fiber diameters and geared towards soft tissue engineering.