G
Gianella Facchin
Researcher at University of the Republic
Publications - 40
Citations - 945
Gianella Facchin is an academic researcher from University of the Republic. The author has contributed to research in topics: Crystal structure & Phenanthroline. The author has an hindex of 16, co-authored 36 publications receiving 778 citations. Previous affiliations of Gianella Facchin include National University of the Littoral & National University of La Plata.
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Journal ArticleDOI
Serum selenium and glutathione peroxidase-3 activity: biomarkers of systemic inflammation in the critically ill?
William Manzanares,Alberto Biestro,Federico Galusso,María H. Torre,Nelly Mañay,Gustavo Pittini,Gianella Facchin,Gil Hardy +7 more
TL;DR: Systemic inflammatory response syndrome and MODS were associated with early decreases in [Se] and [GPx-3] after ICU admission, which may aid future selection of patients who could benefit from Se supplementation.
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Copper complexes with heterocyclic sulfonamides: synthesis, spectroscopic characterization, microbiological and SOD-like activities: crystal structure of [Cu(sulfisoxazole)2(H2O)4] . 2H2O.
Eduardo Kremer,Gianella Facchin,E. Estévez,P. Alborés,Enrique J. Baran,Javier Ellena,María H. Torre +6 more
TL;DR: The synthesis, characterization and comparative biological study of a series of antibacterial copper complexes with heterocyclic sulfonamides were reported, showing that the 3H2O presented the highest antimicrobial potency and a superoxide dismutase-like activity comparable with pharmacological active compounds.
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High-dose selenium reduces ventilator-associated pneumonia and illness severity in critically ill patients with systemic inflammation
William Manzanares,Alberto Biestro,María H. Torre,Federico Galusso,Gianella Facchin,Gil Hardy +5 more
TL;DR: High-dose parenteral selenite significantly increases Se status, improves illness severity, and lowers incidence of hospital-acquired pneumonia including early VAP for SIRS patients in ICU, without short-term adverse events.
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Development of copper(II)-diimine-iminodiacetate mixed ligand complexes as potential antitumor agents
Natalia Alvarez,Luis F.S. Mendes,M. Gabriela Kramer,María H. Torre,Antonio J. Costa-Filho,Javier Ellena,Gianella Facchin +6 more
TL;DR: In this article, the synthesis and characterization of eight compounds with general formula [Cu(iminodiacetate)(diimine)(H2O)x], with x = 0 or 1, and their cytotoxic activities against tumor cells were presented.
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Synthesis and characterization of three new Cu(II)-dipeptide complexes.
Gianella Facchin,María H. Torre,Eduardo Kremer,Oscar E. Piro,Eduardo E. Castellano,Enrique J. Baran +5 more
TL;DR: Three new copper(II) complexes of stoichiometry [Cu(L-dipeptide)].nH(2)O, containing as ligands the dipeptides L-alanine-L-isoleucine, L-Alanine- L-threonine and L-al-tyrosine were prepared and characterized by single crystal X-ray diffractometry, and electronic and infrared spectroscopy.