G
Gisele Facholi Bomfim
Researcher at Universidade Federal de Mato Grosso
Publications - 30
Citations - 561
Gisele Facholi Bomfim is an academic researcher from Universidade Federal de Mato Grosso. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 10, co-authored 20 publications receiving 380 citations. Previous affiliations of Gisele Facholi Bomfim include Georgia Regents University & University of São Paulo.
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Journal ArticleDOI
Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive rats
Gisele Facholi Bomfim,Gisele Facholi Bomfim,Rosangela A. dos Santos,Maria Aparecida Oliveira,Fernanda R. Giachini,Eliana Hiromi Akamine,Rita C. Tostes,Zuleica Bruno Fortes,R. Clinton Webb,Maria Helena Catelli de Carvalho +9 more
TL;DR: The results suggest that TLR4 activation contributes to increased blood pressure, low grade inflammation and plays a role in the augmented vascular contractility displayed by SHR.
Journal ArticleDOI
The interplay between Angiotensin II, TLR4 and hypertension.
Vinicia C. Biancardi,Gisele Facholi Bomfim,Wagner Luis Reis,Sarah Al-Gassimi,Kenia Pedrosa Nunes +4 more
TL;DR: Mechanisms linking Angiotensin II and the innate immune system, in the pathogenesis of hypertension, are discussed.
Journal ArticleDOI
Interleukin-10 limits increased blood pressure and vascular RhoA/Rho-kinase signaling in angiotensin II-infused mice
Victor V. Lima,Saiprasad M. Zemse,Chin Wei Chiao,Gisele Facholi Bomfim,Rita C. Tostes,R. Clinton Webb,Fernanda R. Giachini +6 more
TL;DR: These results demonstrate that IL-10 counteracts both the pressoric activity of Ang II as well as vascular dysfunction associated with hypertension, partially, modulating the RhoA-Rho kinase pathway.
Journal ArticleDOI
Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage
Tiago J. Costa,Simone R. Potje,Thais Fernanda de Campos Fraga-Silva,Julio Alves Silva-Neto,Paula R. Barros,Daniel N.S. Rodrigues,Mirele R. Machado,Ronaldo B. Martins,Rosangela Aparecida Santos-Eichler,Maira N. Benatti,Keyla Santos Guedes de Sá,Carlos Eduardo L. Almado,Italo A. Castro,Marjorie Cornejo Pontelli,Leonardo La Serra,Fernando S. Carneiro,Christiane Becari,Paulo Louzada-Junior,Renê Donizeti Ribeiro de Oliveira,Dario S. Zamboni,Eurico Arruda,Maria Auxiliadora-Martins,Fernanda R. Giachini,Vânia Luiza Deperon Bonato,Natasha E. Zachara,Gisele Facholi Bomfim,Rita C. Tostes +26 more
TL;DR: In this paper, the involvement of TLR9 in SARS-Cov-2-induced endothelial dysfunction and potential contribution to cardiovascular complications in COVID-19 have not been demonstrated.
Journal ArticleDOI
Are the innate and adaptive immune systems setting hypertension on fire
TL;DR: Experimental and clinical evidence demonstrating the contribution of the innate and adaptive immune systems to the development of hypertension is focused on.