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Giuseppe Paolisso
Researcher at Seconda Università degli Studi di Napoli
Publications - 518
Citations - 36557
Giuseppe Paolisso is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Insulin & Diabetes mellitus. The author has an hindex of 85, co-authored 479 publications receiving 33028 citations. Previous affiliations of Giuseppe Paolisso include National Institutes of Health & University of Udine.
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Journal ArticleDOI
Elevated plasma activator inhibitor 1 is not related to insulin resistance and to gene polymorphism in healthy centenarians.
Maria Rosaria Rizzo,Emilia Ragno,Michelangela Barbieri,Domenico De Lucia,Daniela Manzella,Maria Tagliamonte,Donatella Colaizzo,Maurizio Margaglione,Giuseppe Paolisso +8 more
TL;DR: It is demonstrated that in healthy centenarians, plasma PAI-1 were not associated with the degree of insulin resistance as in aged subjects, and Frequency of PAi-1 genotype does not provide an explanation for such differences between aged subjects and centenarian.
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Angiotensin receptor/Neprilysin inhibitor effects in CRTd non-responders: from epigenetic to clinical beside.
Celestino Sardu,Massimo Massetti,Lucia Scisciola,Maria Consiglia Trotta,Matteo Santamaria,M Volpicelli,Valentino Ducceschi,Giuseppe Signoriello,Nunzia D'Onofrio,Ludovica Vittoria Marfella,F Casolaro,M.D. Amico,Alfonso Ruocco,Maria Luisa Balestrieri,Ciro Mauro,Concetta Rafaniello,Annalisa Capuano,Giuseppe Paolisso,Raffaele Marfella +18 more
TL;DR: In this paper , the authors evaluated whether Angiotensin receptor/Neprilysin inhibitors (ARNI) reduce heart failure hospitalizations and deaths in cardiac resynchronization therapy with defibrillator (CRTd) non-responders patients at 12 months of follow-up, modulating microRNAs (miRs) implied in adverse cardiac remodeling.
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Is the aging heart similar to the diabetic heart? Evaluation of LV function of the aging heart with Tissue Doppler Imaging
TL;DR: The rise in IRT in the aging healthy heart is dependent on diastolic LV dysfunction consequent upon the formation of Advanced Glycosilation End-product (AGE) crosslinks with connectival proteins of interstitial myocardial tissue.
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Glycemic control with an artificial pancreas improves insulin responses to both oral and I.V. Glucose in nonobese noninsulin-dependent diabetic subjects
Dario Giugliano,Paolo Di Pinto,Antonio Ceriello,Giuseppe Paolisso,Franco Saccomanno,Roberto Torella,Felice D'Onofrio +6 more
TL;DR: It is indicated that glycemic control with an artificial pancreas improves insulin response to glucose, suggesting that chronic hyperglycemia may stress the impaired B-cell secretory capacity of diabetes.
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Different prevalence of metabolic control and chronic complication rate according to the time of referral to a diabetes care unit in the elderly
TL;DR: A better and more efficient organisation has to be developed, including a strong interaction among GPs, diabetes specialists, and elderly people with T2DM allowing the latter to take charge of their own disease management through a sustained empowerment policy.