G
Giuseppe Paolisso
Researcher at Seconda Università degli Studi di Napoli
Publications - 518
Citations - 36557
Giuseppe Paolisso is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Insulin & Diabetes mellitus. The author has an hindex of 85, co-authored 479 publications receiving 33028 citations. Previous affiliations of Giuseppe Paolisso include National Institutes of Health & University of Udine.
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Journal ArticleDOI
Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI study
Marcello Maggio,Fulvio Lauretani,Gian Paolo Ceda,Stefania Bandinelli,Shehzad Basaria,Giuseppe Paolisso,Alessandro Ble,Josephine M. Egan,E. Jeffrey Metter,Angela Marie Abbatecola,Giovanni Zuliani,Carmelinda Ruggiero,Giorgio Valenti,Jack M. Guralnik,Luigi Ferrucci +14 more
TL;DR: In older women, SHBG is negatively associated with MetS independently of confounders, including inflammatory markers and insulin resistance, and the notion that raising SH BG is a potential therapeutic target for prevention and treatment is supported.
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Glycated ACE2 receptor in diabetes: open door for SARS-COV-2 entry in cardiomyocyte.
Nunzia D'Onofrio,Lucia Scisciola,Celestino Sardu,Maria Consiglia Trotta,Marisa De Feo,Ciro Maiello,Pasquale Mascolo,Francesco De Micco,Fabrizio Turriziani,Emilia Municinò,Pasquale Monetti,Antonio Lombardi,Maria Napolitano,Federica Zito Marino,Andrea Ronchi,Vincenzo Grimaldi,Anca Hermenean,Maria Rosaria Rizzo,Michelangela Barbieri,Renato Franco,Carlo Pietro Campobasso,Claudio Napoli,Maurizio Municinò,Giuseppe Paolisso,Maria Luisa Balestrieri,Raffaele Marfella +25 more
TL;DR: In this paper, the authors investigated the role of diabetic patients in SARS-CoV-2 entry in cardiomyocytes and found that upregulation of ACE2 expression (total and glycosylated forms) in DM patients, along with nonenzymatic glycation, could increase the susceptibility to COVID-19 infection.
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Sex hormone binding globulin levels across the adult lifespan in women — The role of body mass index and fasting insulin
Marcello Maggio,Fabrizio Lauretani,Shehzad Basaria,Gian Paolo Ceda,Stefania Bandinelli,E. J. Metter,A. Bos,Carmelinda Ruggiero,Graziano Ceresini,Giuseppe Paolisso,Andrea Artoni,Giorgio Valenti,J. M. Guralnik,Luigi Ferrucci +13 more
TL;DR: Serum SHBG levels showed a U-shaped trajectory with age, declining from the 2nd to the 6 fourth decade of life and increasing after the 6th decade (p<0.0001), suggesting that BMI and insulin negatively influence SHBG concentration.
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Hyperglycaemia on admission to hospital and COVID-19.
Celestino Sardu,Nunzia D'Onofrio,Maria Luisa Balestrieri,Michelangela Barbieri,Maria Rosaria Rizzo,Vincenzo Messina,Paolo Maggi,Nicola Coppola,Giuseppe Paolisso,Raffaele Marfella +9 more
TL;DR: It is hypothesised that achievement of rapid control of hyperglycaemia in the first 24 h may improve outcomes, and an over-activation of the innate immune system may be responsible for poorer outcomes inhyperglycaemic patients affected by COVID-19.
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FFAs and QT intervals in obese women with visceral adiposity: effects of sustained weight loss over 1 year.
Graziamaria Corbi,Scipione Carbone,P Ziccardi,Giovanni Giugliano,Raffaele Marfella,Francesco Nappo,Giuseppe Paolisso,Katherine Esposito,Dario Giugliano +8 more
TL;DR: The data suggest that the QTc interval is tightly correlated with plasma FFA levels; shortening of cardiac repolarization times in the course of long-lasting weight reduction may reduce the risk of ventricular electrical instability, especially in women with abdominal adiposity.