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Giuseppe Paolisso
Researcher at Seconda Università degli Studi di Napoli
Publications - 518
Citations - 36557
Giuseppe Paolisso is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Insulin & Diabetes mellitus. The author has an hindex of 85, co-authored 479 publications receiving 33028 citations. Previous affiliations of Giuseppe Paolisso include National Institutes of Health & University of Udine.
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Journal ArticleDOI
Management of diabetes in older adults.
Giorgio Sesti,R. Antonelli Incalzi,Enzo Bonora,A. Consoli,A. Giaccari,Stefania Maggi,Giuseppe Paolisso,Francesco Purrello,Gianluigi Vendemiale,Nicola Ferrara +9 more
TL;DR: This review evaluates the currently available hypoglycemic drugs and the current indications to the Italian diabetology community, specifically with regard to the treatment of adults aged 75 years or older with diabetes, including the unmet needs by the guidelines.
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Renin-Angiotensin System and Coronavirus Disease 2019: A Narrative Review
Annamaria Mascolo,Cristina Scavone,Concetta Rafaniello,Carmen Ferrajolo,Giorgio Racagni,Liberato Berrino,Giuseppe Paolisso,Francesco Rossi,Annalisa Capuano +8 more
TL;DR: RAS may play a role in SARS-COV-2-induced cardiac and pulmonary damage, and pharmacological strategies that interfere with the viral attachment to ACE2 or that modulate the RAS are in clinical development for COVID-19.
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Antidiabetic oral treatment in older people: does frailty matter?
Angela Marie Abbatecola,Giuseppe Paolisso,Andrea Corsonello,Silvia Bustacchini,Fabrizia Lattanzio +4 more
TL;DR: Clinical evidence shows that the use of sulfonylureas is associated with a greater risk of hypoglycaemica, whereas metformin and α-glucosidase inhibitors are associated with an increased risk of adverse gastrointestinal effects, so underappreciated risk factors have an important impact on oral antidiabetic treatment options.
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Low Plasma Insulin-Like Growth Factor-1 Concentrations Predict Worsening of Insulin-Mediated Glucose Uptake in Older People
Giuseppe Paolisso,Maria Tagliamonte,Maria Rosaria Rizzo,Carlo Carella,Antonio Gambardella,Michelangela Barbieri,Michele Varricchio +6 more
TL;DR: The predictive role that low plasma IGF‐1 concentration may have on insulin‐ mediated glucose uptake in older persons and insulin like growth factor‐1 levels was investigated.
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l-arginine but not d-arginine stimulates insulin-mediated glucose uptake
Giuseppe Paolisso,Maria Tagliamonte,Raffaele Marfella,Giovanni Verrazzo,Felice D'Onofrio,Dario Giugliano +5 more
TL;DR: Nitric oxide (NO), the metabolic mediator for L-arginine, potentiates insulin-mediated glucose uptake through the increase in blood flow, and an independent effect of intracellular cGMP on WBGD cannot be ruled out.