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Giuseppe Paolisso

Researcher at Seconda Università degli Studi di Napoli

Publications -  518
Citations -  36557

Giuseppe Paolisso is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Insulin & Diabetes mellitus. The author has an hindex of 85, co-authored 479 publications receiving 33028 citations. Previous affiliations of Giuseppe Paolisso include National Institutes of Health & University of Udine.

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Journal Article

Insulin resistance in cognitive impairment: the InCHIANTI study

C. Geroldi, +8 more
- 01 Jan 2005 - 
TL;DR: In this paper, the association between cognitive impairment, with and without subcortical features, and insulin resistance in an elderly community-dwelling population was tested. But the results were limited to individuals who had experienced stroke.
Book ChapterDOI

Cognitive Decline and Diabetes: A Focus on Linking Mechanisms

Michelangela Barbieri, +2 more
- 01 Jan 2014 - 
TL;DR: Hyperinsulinemia, IR, and other related conditions such as hypertension, dyslipidemia, and subclinical inflammation are related to a higher risk of cognitive impairment and dementia among diabetic patients, including mainly vascular dementia and late onset Alzheimer’s disease (LOAD).
Journal Article

Metabolic effects of nitrendipine.

Giuseppe Paolisso, +4 more
- 01 Nov 1991 - 
TL;DR: In the nitrendipine-treated patients, both systolic and diastolic blood pressures were reduced significantly during treatment (from a mean of 180 to 155mmHg and 92 to 80 mmHg); heart rate did not change significantly; and results of a posttreatment oral glucose tolerance test were similar in the two treatment groups.
Journal ArticleDOI

Cirrhosis and frailty assessment in elderly patients: A paradoxical result.

Alessandro Federico, +7 more
- 01 Jan 2020 - 
TL;DR: Clinical implication of this finding is that frailty assessment performed in the well-compensated liver cirrhosis patient can identify those cirrhotic patients who may benefit from tailored interventions similarly to non-cirrhotic elderly patients.
Journal ArticleDOI

SIRT3 mediates the effects of PCSK9 inhibitors on inflammation, autophagy, and oxidative stress in endothelial cells

Nunzia D'Onofrio, +11 more
- 01 Jan 2023 - 
TL;DR: In this paper , human aortic endothelial cells (TeloHAEC) were pre-treated with 100 µg/mL of the PCSK9i evolocumab and then exposed to 20 ng/mL IL-6, a major driver of cardiovascular diseases (CVD), in both naïve state and after siRNA-mediated suppression of the NAD-dependent deacetylase sirtuin-3 (SIRT3).