G
Graham C. Walker
Researcher at Massachusetts Institute of Technology
Publications - 386
Citations - 39252
Graham C. Walker is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Sinorhizobium meliloti & DNA polymerase. The author has an hindex of 93, co-authored 381 publications receiving 36875 citations. Previous affiliations of Graham C. Walker include Norwich Research Park & University of California, Santa Cruz.
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DNA Repair and Mutagenesis
TL;DR: Nucleotide excision repair in mammalian cells: genes and proteins Mismatch repair The SOS response and recombinational repair in prokaryotes Mutagenesis in proKaryote Mutagenisation in eukaryotes Other DNA damage tolerance responses in eUKaryotes.
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Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli.
TL;DR: Comparing the SOS, Heat Shock, and Adaptive Regulatory Systems and evidence suggesting that UV mutagenesis does not require the induction of genes other than those repressed by LexA, the role of SOS processing to the spontaneous mutation frequency is suggested.
Journal ArticleDOI
A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance
Thien-Fah Mah,Betsey Pitts,Brett J. Pellock,Brett J. Pellock,Graham C. Walker,Philip S. Stewart,George A. O'Toole +6 more
TL;DR: The results indicate that biofilms themselves are not simply a diffusion barrier to these antibiotics, but rather that bacteria within these microbial communities employ distinct mechanisms to resist the action of antimicrobial agents.
Journal ArticleDOI
Mechanisms of DNA damage, repair, and mutagenesis.
TL;DR: This introductory review will delineate mechanisms of DNA damage and the counteracting repair/tolerance pathways to provide insights into the molecular basis of genotoxicity in cells that lays the foundation for subsequent articles in this issue.
Journal ArticleDOI
The Y-Family of DNA Polymerases
Haruo Ohmori,Errol C. Friedberg,Robert P. P. Fuchs,Myron F. Goodman,Fumio Hanaoka,David C. Hinkle,Thomas A. Kunkel,Christopher W. Lawrence,Zvi Livneh,Takehiko Nohmi,Louise Prakash,Satya Prakash,Takeshi Todo,Graham C. Walker,Zhigang Wang,Roger Woodgate +15 more
TL;DR: The unrooted phylogenetic tree shown in Figure 1 shows the progression of tree-like structures formed over time in the presence of E.coli and shows the relationships between E. Coli and Tournaisian trees.