The Y-Family of DNA Polymerases
Haruo Ohmori,Errol C. Friedberg,Robert P. P. Fuchs,Myron F. Goodman,Fumio Hanaoka,David C. Hinkle,Thomas A. Kunkel,Christopher W. Lawrence,Zvi Livneh,Takehiko Nohmi,Louise Prakash,Satya Prakash,Takeshi Todo,Graham C. Walker,Zhigang Wang,Roger Woodgate +15 more
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TLDR
The unrooted phylogenetic tree shown in Figure 1 shows the progression of tree-like structures formed over time in the presence of E.coli and shows the relationships between E. Coli and Tournaisian trees.About:
This article is published in Molecular Cell.The article was published on 2001-07-01 and is currently open access. It has received 864 citations till now. The article focuses on the topics: Phylogenetic tree & Phylogenetics.read more
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Eukaryotic translesion synthesis DNA polymerases: Specificity of structure and function
TL;DR: This review focuses on eukaryotic translesion synthesis (TLS) DNA polymerases, and the emphasis is on Saccharomyces cerevisiae and human Y- family polymerases (Pols) eta, iota, kappa, and Rev1, as well as on Polzeta, which is a member of the B-family polymerases.
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Interaction of Human DNA Polymerase η with Monoubiquitinated PCNA: A Possible Mechanism for the Polymerase Switch in Response to DNA Damage
TL;DR: This work shows that, in human cells, PCNA becomes monoubiquitinated following UV irradiation of the cells and that this is dependent on the hRad18 protein, and identifies two motifs in poleta that are involved in this interaction.
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Error-prone repair DNA polymerases in prokaryotes and eukaryotes.
TL;DR: This review is devoted primarily to a discussion of Y-family polymerase members that exhibit error-prone behavior, which poses challenging questions about their roles in targeting and trafficking.
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Mutations induced by ultraviolet light
TL;DR: It is shown that CPDs (rather than 6-4 photoproducts or other lesions) are responsible for the great majority of UVB-induced mutations and the role of DNA damage-tolerant DNA polymerases in UV lesion bypass and mutagenesis is discussed.
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Stress-Induced Mutagenesis in Bacteria
Ivana Bjedov,Ivana Bjedov,Olivier Tenaillon,Olivier Tenaillon,Bénédicte Gérard,Bénédicte Gérard,Valeria Souza,Valeria Souza,Erick Denamur,Erick Denamur,Miroslav Radman,Miroslav Radman,François Taddei,François Taddei,Ivan Matic,Ivan Matic +15 more
TL;DR: It is suggested that irrespective of the causes of their emergence, stress-induced mutations participate in adaptive evolution and could be a by-product of genetic strategies for improving survival under stress.
References
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Compilation, alignment, and phylogenetic relationships of DNA polymerases
Dan Braithwaite,Junetsu Ito +1 more
TL;DR: This is an update of an earlier compilation and alignment of DNA polymerase sequences (Ito and Braithwaite, 1991) that attempted to compile complete sequences, to facilitate the identification of conserved and viable regions of the DNA polymerases.
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Compilation and alignment of DNA polymerase sequences.
Junetsu Ito,Dan Braithwaite +1 more
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Archaeal DNA Replication: Identifying the Pieces to Solve a Puzzle
TL;DR: This review summarizes the present knowledge about archaeal DNA polymerases and their relationship with those accessory proteins, which were predicted from the genome sequences.