G
Guillaume Arras
Researcher at PSL Research University
Publications - 12
Citations - 2911
Guillaume Arras is an academic researcher from PSL Research University. The author has contributed to research in topics: Exosome & Mitosis. The author has an hindex of 8, co-authored 11 publications receiving 2095 citations. Previous affiliations of Guillaume Arras include Curie Institute.
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Journal ArticleDOI
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.
Joanna Kowal,Guillaume Arras,Marina Colombo,Mabel Jouve,Jakob Paul Morath,Bjarke Primdal-Bengtson,Florent Dingli,Damarys Loew,Mercedes Tkach,Clotilde Théry +9 more
TL;DR: This work demonstrates the presence of exosomal and nonexosomal subpopulations within small EVs, and proposes their differential separation by immuno-isolation using either CD63, CD81, or CD9, and provides guidelines to define subtypes of EVs for future functional studies.
Journal ArticleDOI
Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo.
Frederik J. Verweij,Frederik J. Verweij,Céline Revenu,Guillaume Arras,Florent Dingli,Damarys Loew,D. Michiel Pegtel,Gautier Follain,Guillaume Allio,Jacky G. Goetz,Pascale Zimmermann,Philippe Herbomel,Filippo Del Bene,Graça Raposo,Guillaume van Niel +14 more
TL;DR: This work developed an in vivo model to study EV function by expressing CD63-pHluorin in zebrafish embryos with high spatiotemporal accuracy, demonstrating functional inter-organ communication by exosomes.
Journal ArticleDOI
Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.
Antoine Forget,Antoine Forget,Loredana Martignetti,Stéphanie Puget,Laurence Calzone,Sebastian Brabetz,Daniel Picard,Arnau Montagud,Stéphane Liva,Alexandre Sta,Florent Dingli,Guillaume Arras,Jaime Rivera,Damarys Loew,Aurore Besnard,Joelle Lacombe,Mélanie Pagès,Pascale Varlet,Christelle Dufour,Hua Yu,Hua Yu,Audrey Mercier,Audrey Mercier,Emilie Indersie,Emilie Indersie,Anaïs Chivet,Anaïs Chivet,Sophie Leboucher,Sophie Leboucher,Laura Sieber,Kevin Beccaria,Michael Gombert,Frauke Meyer,Nan Qin,Jasmin Bartl,Lukas Chavez,Konstantin Okonechnikov,Tanvi Sharma,Venu Thatikonda,Franck Bourdeaut,Celio Pouponnot,Celio Pouponnot,Vijay Ramaswamy,Andrey Korshunov,Arndt Borkhardt,Guido Reifenberger,Patrick Poullet,Michael D. Taylor,Marcel Kool,Stefan M. Pfister,Stefan M. Pfister,Daisuke Kawauchi,Emmanuel Barillot,Marc Remke,Olivier Ayrault,Olivier Ayrault +55 more
TL;DR: Proteomic and phosphoproteomic analyses identify aberrant ERBB4-SRC signaling in group 4 and unveils an oncogenic pathway and potential therapeutic vulnerability in the most common medulloblastoma subgroup.
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Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.
Matteo Fossati,Nora Assendorp,Olivier Gemin,Sabrina Colasse,Florent Dingli,Guillaume Arras,Damarys Loew,Cécile Charrier +7 more
TL;DR: GluD1 defines a trans-synaptic interaction regulating postsynaptic signaling pathways for the proper establishment of cortical inhibitory connectivity and challenges the dichotomy between iGluRs and inhibitory synaptic molecules.
Journal ArticleDOI
Moesin Is a Major Regulator of Centrosome Behavior in Epithelial Cells with Extra Centrosomes
Dora Sabino,Delphine Gogendeau,Davide Gambarotto,Maddalena Nano,Carole Pennetier,Florent Dingli,Guillaume Arras,Damarys Loew,Renata Basto +8 more
TL;DR: A mechanistic explanation for the increased aneuploidy and transformation potential primed by centrosome amplification in epithelial tissues is provided.