G
Guillaume Salbreux
Researcher at Francis Crick Institute
Publications - 86
Citations - 6840
Guillaume Salbreux is an academic researcher from Francis Crick Institute. The author has contributed to research in topics: Cell cortex & Biology. The author has an hindex of 34, co-authored 75 publications receiving 5294 citations. Previous affiliations of Guillaume Salbreux include Max Planck Society & University of Michigan.
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Journal ArticleDOI
Actin cortex mechanics and cellular morphogenesis.
TL;DR: This review summarizes current knowledge on the structural organization, composition, and mechanics of the actin cortex, focusing on the link between molecular processes and macroscopic physical properties and consequences of cortex dysfunction in disease.
Journal ArticleDOI
Role of cortical tension in bleb growth
Jean-Yves Tinevez,Ulrike Schulze,Guillaume Salbreux,Julia Roensch,Jean-François Joanny,Ewa K. Paluch +5 more
TL;DR: It is shown that there is a critical tension below which blebs cannot expand, and this dependence can be fitted with a model of the cortex as an active elastic material, and insights are provided as to how bleb formation can be biochemically regulated during cell motility.
Journal ArticleDOI
Adhesion functions in cell sorting by mechanically coupling the cortices of adhering cells.
Jean-Léon Maître,Hélène Berthoumieux,Hélène Berthoumieux,Simon Frederik Gabriel Krens,Guillaume Salbreux,Frank Jülicher,Ewa K. Paluch,Carl-Philipp Heisenberg +7 more
TL;DR: It is shown that cell adhesion and cortex tension have different mechanical functions in controlling progenitor cell-cell contact formation and sorting during zebrafish gastrulation.
Journal ArticleDOI
Forces Driving Epithelial Spreading in Zebrafish Gastrulation
Martin Behrndt,Guillaume Salbreux,Pedro Campinho,Robert Hauschild,Felix Oswald,Julia Roensch,Stephan W. Grill,Carl-Philipp Heisenberg +7 more
TL;DR: It is shown that the spreading of the enveloping cell layer (EVL) over the yolk cell during zebrafish gastrulation is driven by a contractile actomyosin ring, and that this ring functions not only by circumferential contraction but also by a flow-friction mechanism.
Journal ArticleDOI
Actin cortex architecture regulates cell surface tension
Priyamvada Chugh,Andrew G. Clark,Andrew G. Clark,Matthew B. Smith,Davide A. D. Cassani,Kai Dierkes,Anan Ragab,Philippe P. Roux,Guillaume Charras,Guillaume Charras,Guillaume Salbreux,Ewa K. Paluch +11 more
TL;DR: It is shown that the actin filament length regulators CFL1, CAPZB and DIAPH1 regulate mitotic cortex thickness and that both increasing and decreasing thickness decreases tension in mitosis.