G
Guillermo Díaz-Araya
Researcher at University of Chile
Publications - 91
Citations - 13233
Guillermo Díaz-Araya is an academic researcher from University of Chile. The author has contributed to research in topics: Receptor & Heart failure. The author has an hindex of 31, co-authored 84 publications receiving 10695 citations. Previous affiliations of Guillermo Díaz-Araya include Pontifical Catholic University of Chile & Valparaiso University.
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Journal ArticleDOI
Oxidative stress in pericardial fluid and plasma and its association with ventricular function.
José Luis Vukasovic,Francisco Moraga,Guillermo Díaz-Araya,Eduardo Turner,Mario Chiong,Polentzi Uriarte,Fernando Florenzano,Sergio Lavandero +7 more
TL;DR: Plasma and pericardial fluid malondialdehyde levels can be used as an early marker of ventricular dysfunction and this parameter was associated with left ventricular end systolic diameter.
Journal ArticleDOI
TGF-β1 decreases CHOP expression and prevents cardiac fibroblast apoptosis induced by endoplasmic reticulum stress
Francisco Olivares-Silva,Jenaro Espitia-Corredor,Alan Letelier,Raúl Vivar,Pablo Parra-Flores,Ivonne Olmedo,J. Montenegro,Viviana Pardo-Jiménez,Guillermo Díaz-Araya +8 more
TL;DR: TGF-β1 partially protects CF apoptosis induced by sI/R or Tn, through a mechanism that would involve ER stress.
Journal ArticleDOI
FoxO1 is required for high glucose-dependent cardiac fibroblasts into myofibroblast phenoconversion.
Raúl Vivar,Renatto Anfossi,Claudio Humeres,Mabel Catalán,Christopher Reyes,Simone Cárdenas,Alejandra Contreras,Pablo Aránguiz,Fabiola González,Guillermo Díaz-Araya +9 more
TL;DR: In this article, the effects of FoxO1 pharmacological inhibition on CFs phenoconversion in both in vitro and ex vivo models of DM were investigated, and it was shown that hyperglycemia induces FoxO 1 activation, the increase of CTGF expression, and CFs phenotype change.
Journal ArticleDOI
Scavenging of the one-electron reduction product from nisoldipine with relevant thiols: electrochemical and EPR spectroscopic evidences.
Luis J. Núñez-Vergara,Guillermo Díaz-Araya,Claudio Olea-Azar,Ana María Atria,Soledad Bollo-Dragnic,Juan A. Squella +5 more
TL;DR: Electrochemical and EPR data indicated that all the tested thiols scavenged the nitro radical anion from nisoldipine, significantly higher than the natural decay of the radical in mixed medium.
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Resolvin E1 attenuates doxorubicin-induced cardiac fibroblast senescence: A key role for IL-1β.
Jenaro Espitia-Corredor,Licia S. Shamoon,Francisco Olivares-Silva,Constanza Rimassa-Taré,Claudia Muñoz-Rodríguez,Claudio Espinoza-Pérez,Carlos F. Sánchez-Ferrer,Concepción Peiró,Guillermo Díaz-Araya +8 more
TL;DR: In this paper , Resolvin E1 (RvE1), a lipid derivative resolutive mediator with potent anti-inflammatory effects has not been used before to prevent CFs senescence.