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Binhai Zheng
Researcher at University of California, San Diego
Publications - 89
Citations - 13972
Binhai Zheng is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Axon & Myelin. The author has an hindex of 46, co-authored 81 publications receiving 12301 citations. Previous affiliations of Binhai Zheng include University of California, San Francisco & University of Kentucky.
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Journal ArticleDOI
p63 is a p53 homologue required for limb and epidermal morphogenesis.
TL;DR: P63 is essential for several aspects of ectodermal differentiation during embryogenesis, including hair follicles, teeth and mammary glands, which are absent in p63-deficient mice.
Journal ArticleDOI
Interacting Molecular Loops in the Mammalian Circadian Clock
Lauren P. Shearman,Sathyanarayanan Sriram,David R. Weaver,Elizabeth S. Maywood,Inẽs Chaves,Binhai Zheng,Kazuhiko Kume,Cheng Chi Lee,Gijsbertus T. J. van der,Horst,Michael H. Hastings,Steven M. Reppert +11 more
TL;DR: Analysis of Clock/Clock mutant mice, homozygous Period2(Brdm1) mutants, and Cryptochrome-deficient mice reveals substantially altered Bmal1 rhythms, consistent with a dominant role of PERIOD2 in the positive regulation of the Bmal 1 loop.
Journal ArticleDOI
Nonredundant Roles of the mPer1 and mPer2 Genes in the Mammalian Circadian Clock
Binhai Zheng,Urs Albrecht,Krista Kaasik,Marijke Sage,Weiqin Lu,Sukeshi Vaishnav,Qiu Li,Zhong Sheng Sun,Gregor Eichele,Allan Bradley,Cheng Chi Lee +10 more
TL;DR: The studies show that mPER1 and mPER2 have distinct and complementary roles in the mouse clock mechanism, suggesting independent controls by the two proteins over some output pathways.
Journal ArticleDOI
PTEN deletion enhances the regenerative ability of adult corticospinal neurons
Kai Liu,Yi Lu,Jae K. Lee,Ramsey F. Samara,Rafer Willenberg,Ilse Sears-Kraxberger,Andrea Tedeschi,Kevin K. Park,Duo Jin,Bin Cai,Bengang Xu,Lauren Connolly,Oswald Steward,Binhai Zheng,Zhigang He +14 more
TL;DR: It is found that PTEN/mTOR are critical for controlling the regenerative capacity of mouse corticospinal neurons and modulating neuronal intrinsic PTEN-mTOR activity represents a potential therapeutic strategy for promoting axon regeneration and functional repair after adult spinal cord injury.
Journal ArticleDOI
Reactive astrocyte nomenclature, definitions, and future directions
Carole Escartin,Elena Galea,Andras Lakatos,James P. O'Callaghan,Gabor C. Petzold,Gabor C. Petzold,Alberto Serrano-Pozo,Christian Steinhäuser,Andrea Volterra,Giorgio Carmignoto,Giorgio Carmignoto,Amit Agarwal,Nicola J. Allen,Alfonso Araque,Luis Barbeito,Ari Barzilai,Dwight E. Bergles,Gilles Bonvento,Arthur M. Butt,Wei Ting Chen,Martine Cohen-Salmon,Colm Cunningham,Benjamin Deneen,Bart De Strooper,Bart De Strooper,Blanca Diaz-Castro,Cinthia Farina,Marc R. Freeman,Vittorio Gallo,James E. Goldman,Steven A. Goldman,Steven A. Goldman,Magdalena Götz,Antonia Gutierrez,Philip G. Haydon,Dieter Henrik Heiland,Elly M. Hol,Matthew Holt,Masamitsu Iino,Ksenia V. Kastanenka,Helmut Kettenmann,Baljit S. Khakh,Schuichi Koizumi,C. Justin Lee,Shane A. Liddelow,Brian A. MacVicar,Pierre J. Magistretti,Pierre J. Magistretti,Albee Messing,Anusha Mishra,Anna V. Molofsky,Keith K. Murai,Christopher M. Norris,Seiji Okada,Stéphane H. R. Oliet,João Filipe Oliveira,João Filipe Oliveira,Aude Panatier,Vladimir Parpura,Marcela Pekna,Milos Pekny,Luc Pellerin,Gertrudis Perea,Beatriz G. Pérez-Nievas,Frank W. Pfrieger,Kira E. Poskanzer,Francisco J. Quintana,Richard M. Ransohoff,Miriam Riquelme-Perez,Stefanie Robel,Christine R. Rose,Jeffrey D. Rothstein,Nathalie Rouach,David H. Rowitch,Alexey Semyanov,Alexey Semyanov,Swetlana Sirko,Harald Sontheimer,Raymond A. Swanson,Javier Vitorica,Ina B. Wanner,Levi B. Wood,Jia Qian Wu,Binhai Zheng,Eduardo R. Zimmer,Robert Zorec,Michael V. Sofroniew,Alexei Verkhratsky,Alexei Verkhratsky +88 more
TL;DR: In this article, the authors point out the shortcomings of binary divisions of reactive astrocytes into good-vs-bad, neurotoxic vs-neuroprotective or A1-vs.A2.