Hans Ackerman

TL;DR: The TNF locus in the Gambian and Malawi sample is haplotypically diverse and has a rich history of intragenic recombination, and a large proportion of TNF SNPs must be typed to detect a disease-modifying SNP at this locus.

TL;DR: A weak but significant association of the NOS2A locus with susceptibility to cerebral malaria is indicated, despite high linkage disequilibrium across the region studied, this association would not have been detected without the initial construction of a dense marker set for haplotype tagging.

TL;DR: In this paper, the authors investigated the presence of additional major histocompatibility complex (MHC) susceptibility genes outside the LTA-TNF region that modify the effect of HLA-DRB1 on susceptibility to rheumatoid arthritis.

TL;DR: A Blantyre coma score of 2 or less is the most sensitive and specific clinical feature to predict death or development of neurological sequelae in children with SM, and the BCS is a quantitative predictor of death.

TL;DR: Investigating sequence variation in the proximal 2.6 kb of the inducible nitric oxide synthase promoter and the relationship between SNP haplotypes and a pentanucleotide microsatellite in Gambians and UK Caucasians indicates that LD might be maintained over considerable genetic distance in non-African populations, supporting the use of such ‘mixed marker haplotypes’ in LD-based mapping, and allowing inferences to be drawn about human origins.