Stanley Usen

TL;DR: The reduction in the overall incidence of radiologically defined pneumonia in PRP-T vaccinees suggests that about 20% of episodes of pneumonia in young Gambian children are due to Hib, which should substantially reduce childhood mortality due to pneumonia and meningitis.

TL;DR: These findings provide proof of principle that fine-resolution multipoint imputation, based on population-specific sequencing data, can substantially boost authentic GWA signals and enable fine mapping of causal variants in African populations.

TL;DR: The Gambian Hib immunisation programme reduced the occurrence of Hib disease despite irregular vaccine supply, and has important implications for the introduction of the vaccine into routine immunisation programmes of other developing countries.

TL;DR: The IL8-251A allele resides on two haplotypes, only one of which is associated with disease, suggesting that this may not be the functional allele and that selective pressure may have acted on this locus.

TL;DR: The finding that G6PD deficiency has opposing effects on different fatal complications of P. falciparum infection indicates that the evolutionary origins of this common human genetic disorder are more complex than previously supposed.