H
Hans J. Tanke
Researcher at Leiden University
Publications - 56
Citations - 4377
Hans J. Tanke is an academic researcher from Leiden University. The author has contributed to research in topics: Fluorescence loss in photobleaching & Gene mapping. The author has an hindex of 29, co-authored 56 publications receiving 4238 citations. Previous affiliations of Hans J. Tanke include Erasmus University Rotterdam.
Papers
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Journal ArticleDOI
Characteristics of A spermatogonia and preleptotene spermatocytes in the vitamin A-deficient rat testis.
A. M. M. Van Pelt,F. M. F. Van Dissel-Emiliani,I. C. Gaemers,M. J. M. Van Der Burg,Hans J. Tanke,Dirk G. de Rooij +5 more
TL;DR: It is concluded that in the VAD rat testis, many of the proliferative activity and other characteristics of germ cells in the vitamin A-deficient (VAD) ratTestis degenerate, and the remaining A spermatogonia are the undifferentiated sperMatogonia that are unable to differentiate into A1 sperMATogonia.
Short Communication Molecular Cytogenetic Analysis of Prostatic Adenocarcinomas from Screening Studies Early Cancers May Contain Aggressive Genetic Features
Janneke C. Alers,Pieter-Jaap Krijtenburg,Robert F. Hoedemaeker,Mark F. Wildhagen,Wim C.J. Hop,Theodorus H. van der Kwast,Hans J. Tanke,Herman van Dekken +7 more
TL;DR: In this paper, the European Randomized Study of Screening for Prostate Cancer (ERSC) was used to identify early events in prostatic tumorigenesis, whereas chromosomal gains, especially of 8q, appear to be late events in prostate tumor development.
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Flow cytometry of reticulocytes applied to clinical hematology
TL;DR: Flow cytometry of peripheral blood reticulocytes is a more informative method for the study of hematologic abnormalities than conventional methods forreticulocyte counting and classification.
Journal ArticleDOI
Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization
Joop Wiegant,Vladimir Bezrookove,Carla Rosenberg,Hans J. Tanke,Anton K. Raap,Hongen Zhang,Michael L. Bittner,Jeffrey M. Trent,Paul S. Meltzer +8 more
TL;DR: PQ-COBRA-FISH considerably enhances the ability to determine the composition of rearranged chromosomes as demonstrated by the identification of pericentric inversions and isochromosomes as well as the elucidation of the arm identity of chromosomal material involved in complex translocations that occur in solid tumors.
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Fluorescent dot counting in interphase cell nuclei
TL;DR: A completely automated fluorescence microscope system that counts fluorescent hybridization dots for one probe in interphase cell nuclei and results approximate the results of manual counting are presented.