H
Hans J. Tanke
Researcher at Leiden University
Publications - 56
Citations - 4377
Hans J. Tanke is an academic researcher from Leiden University. The author has contributed to research in topics: Fluorescence loss in photobleaching & Gene mapping. The author has an hindex of 29, co-authored 56 publications receiving 4238 citations. Previous affiliations of Hans J. Tanke include Erasmus University Rotterdam.
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Journal ArticleDOI
Detailed examination of lymph nodes improves prognostication in colorectal cancer
Fania S. Doekhie,Wilma E. Mesker,Peter J. K. Kuppen,Gijs A. van Leeuwen,Hans Morreau,Geertruida H. de Bock,Hein Putter,Hans J. Tanke,Cornelis J.H. van de Velde,Rob A. E. M. Tollenaar +9 more
TL;DR: Lymph node analysis of 2 levels and immunohistochemical staining add to the detection of macrometastases and micrometasts in CRC, which was found to be an independent predictor of disease recurrence.
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Combined flow cytometry and image cytometry of the same cytological sample.
TL;DR: Flow cytometry and image cytometry, two measuring techniques in the field of analytical cytology, can be used sequentially on the same cytological sample to eliminate all artefacts and normal cells.
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A new approach for fluorescence correlation spectroscopy (FCS) based immunoassays.
TL;DR: This work proposes to use a fluorescently-labelled tag which has two crucial properties: its molecular weight is significantly lower than that of an antibody and it is capable to discriminate between free antibodies and immune complexes.
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In vivo monitoring of mRNA movement in Drosophila body wall muscle cells reveals the presence of myofiber domains.
Alice M. C. van Gemert,Annelies M. A. van der Laan,Gonneke S. K. Pilgram,Lee G. Fradkin,Jasprina N. Noordermeer,Hans J. Tanke,Carolina R. Jost +6 more
TL;DR: Data suggest that the domains made visible in experiments result from prolonged interactions with as yet undefined structures close to the nuclei that prevent GFP-tagged mRNAs from rapidly moving between the domains.
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Effect of chromatic errors in microscopy on the visualization of multi-color fluorescence in situ hybridization.
TL;DR: Standard preparations consisting of solutions of defined mixtures of fluorescent dyes or objects stained with defined ratios of fluorophores, are proposed to correct for the errors observed.