Hans Kreipe

TL;DR: Mutations in genes encoding the IL10R subunit proteins were found in patients with early-onset enterocolitis, involving hyperinflammatory immune responses in the intestine, and resulted in disease remission in one patient.

TL;DR: This is the first microRNA profiling of in situ-derived PMF, ET and normal megakaryocytes, indicating that a complex shift of microRNA expression appears to be the underlying defect.

TL;DR: It is concluded that tyrosine kinase Lyn contributes to the malignant phenotype in certain leukaemia subtypes and therefore attracts targeted therapy.

TL;DR: Results demonstrate that the expression of KAI1 is maintained during progression to metastasis in a large proportion of ER‐negative mammary carcinomas, which has significant implications for the use of K AI1 as a clinical marker and the understanding of the metastatic process in human breast cancer.

TL;DR: Investigation in an unselected series of breast cancer patients the value of incorporating morphological and immunohistochemical features for the selection of patients who may benefit from BRCA1 genetic testing found no significant difference between tumors of mutation carriers and noncarriers.