Hans Lehrach

TL;DR: This work shows that song behaviour engages gene regulatory networks in the zebra finch brain, altering the expression of long non-coding RNAs, microRNAs, transcription factors and their targets and shows evidence for rapid molecular evolution in the songbird lineage of genes that are regulated during song experience.

TL;DR: It is demonstrated that knowing the transcript's orientation allows more accurate determination of the structure and expression of genes and helps to identify new genes and enables studying promoter-associated and antisense transcription.

TL;DR: In the absence of signal saturation or background noise, it is believed that short-read sequencing technologies will have a major impact on gene expression studies in the near future.

TL;DR: A method for the synthesis of oligonucleotides with block structure (padlock probes, primers for multiplex polymerase chain reaction (PCR), and ligation-independent cloning), based on the ligation of presynthesized parts by T4 DNA ligase is described.