Hatice Hasturk

TL;DR: Current knowledge of the host response in periodontitis is delineated to delineate the role of innate immunity, the failure of acute inflammation to resolve (thus becoming chronic), the cytokine pathways that regulate the activation of acquired immunity and the cells and products of the immune system are considered.

TL;DR: Patients with RP presented a distinct microbial profile compared to patients in the GR and PH groups, as determined by HOMIM.

TL;DR: PRP is a rich source of growth factors and promoted significant changes in monocyte-mediated proinflammatory cytokine/chemokine release and lipoxin A(4) (LXA(4)) generation, suggesting that PRP may suppress cytokine release, limit inflammation, and, thereby, promote tissue regeneration.

TL;DR: This report is the first to show that resolution of inflammation by a naturally occurring endogenous lipid mediator results in complete regeneration of pathologically lost tissues, including bone.

TL;DR: Topical application of RvE1 in rabbit periodontitis conferred dramatic protection against inflammation induced tissue and bone loss associated withperiodontitis.