H
Hector Estevez
Researcher at Complutense University of Madrid
Publications - 9
Citations - 372
Hector Estevez is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Immune system & Vitamin D and neurology. The author has an hindex of 5, co-authored 9 publications receiving 251 citations.
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Journal ArticleDOI
Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae
Alfonso Olaya-Abril,Rafael Prados-Rosales,Michael J. McConnell,Reyes Martín-Peña,José A. González-Reyes,Irene Jiménez-Munguía,Lidia Gómez-Gascón,Javier Burón Fernández,Jose L. Luque-Garcia,Carlos García-Lidón,Hector Estevez,Jerónimo Pachón,Ignacio Obando,Arturo Casadevall,Liise Anne Pirofski,Manuel J. Rodríguez-Ortega,Manuel J. Rodríguez-Ortega +16 more
TL;DR: This work demonstrates the active production of vesicle production by Streptococcus pneumoniae from the plasma membrane, rather than being a product from cell lysis, and shows that pneumococcus produces membrane-derived vesicles particularly enriched in lipoproteins and short-chain fatty acids.
Journal ArticleDOI
Effects of chitosan-stabilized selenium nanoparticles on cell proliferation, apoptosis and cell cycle pattern in HepG2 cells: comparison with other selenospecies.
TL;DR: The bioanalytical characterization of different parameters such as cell proliferation, apoptosis and cell cycle pattern on HepG2 cells has shown the unique properties of this relatively novel compound that support and complete prior evidences for future applications as chemotherapeutic agent.
Journal ArticleDOI
Antimycobacterial effect of selenium nanoparticles on Mycobacterium tuberculosis.
Hector Estevez,Ainhoa Palacios,David Gil,Juan Anguita,María Vallet-Regí,Blanca González,Rafael Prados-Rosales,Jose L. Luque-Garcia +7 more
TL;DR: The results showed that SeNPs are able to inhibit the growth of both types of mycobacteria by damaging their cell envelope integrity, which opens a new opportunity for the use of this type of nanoparticles as antimycobacterial agents by themselves, or for the development of novel nanosystems that combine the action of these nanoparticles with other drugs.
Journal ArticleDOI
Acetate correlates with disability and immune response in multiple sclerosis.
Silvia Pérez-Pérez,Maria Inmaculada Dominguez-Mozo,Aitana Alonso-Gómez,Silvia Medina,Noelia Villarrubia,Jose Ignacio Fernández-Velasco,María Ángel García-Martínez,Estefania Garcia-Calvo,Hector Estevez,Lucienne Costa-Frossard,José C. Álvarez-Cermeño,Jose L. Luque-Garcia,Rafael Arroyo,Luisa M. Villar,Roberto Alvarez-Lafuente +14 more
TL;DR: In MS there exists a correlation between plasma acetate levels, EDSS and increased IL-17+ T cells, and future studies will elucidate the role of SCFA in the disease.
Journal ArticleDOI
How oral probiotics affect the severity of an experimental model of progressive multiple sclerosis? Bringing commensal bacteria into the neurodegenerative process.
Leyre Mestre,Francisco J. Carrillo-Salinas,Francisco J. Carrillo-Salinas,Ana Feliú,Miriam Mecha,Graciela Alonso,Carmen Espejo,Laura Calvo-Barreiro,Jose L. Luque-Garcia,Hector Estevez,Luisa M. Villar,Carmen Guaza +11 more
TL;DR: The effects of Vivomixx on the gut microbiome and central and peripheral immune responses in a murine model of primary progressive MS reinforce the beneficial effects of oral probiotics that would be coadjuvant treatments to current MS therapies.