H
Heidi G. Sutherland
Researcher at Queensland University of Technology
Publications - 94
Citations - 4788
Heidi G. Sutherland is an academic researcher from Queensland University of Technology. The author has contributed to research in topics: Migraine & Population. The author has an hindex of 24, co-authored 85 publications receiving 4282 citations. Previous affiliations of Heidi G. Sutherland include University of Sydney & Griffith University.
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Journal ArticleDOI
Epigenetic inheritance at the agouti locus in the mouse.
TL;DR: It is demonstrated here that this maternal epigenetic effect is not the result of a maternally contributed environment, and results from incomplete erasure of an epigenetic modification when a silenced Avy allele is passed through the female germ line, with consequent inheritance of the epigenetic modified.
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Transcription factories: gene expression in unions?
TL;DR: In this article, the experimental evidence in support of the transcription factory model and the evidence that argues against such a spatially structured view of transcription are discussed. But, this concept is not universally accepted.
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Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
TL;DR: The PWWP domain of the chromatin-associated protein Psip1/Ledgf can specifically recognize tri-methylated H3K36 and that, like this histone modification, thePsip1 short (p52) isoform is enriched at active genes.
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Localization of a putative transcriptional regulator (atrx) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes
T. L. McDowell,Richard J. Gibbons,Heidi G. Sutherland,Delia O'Rourke,Wendy A. Bickmore,Ana Pombo,H. Turley,K. Gatter,David J. Picketts,Veronica J. Buckle,Lynda Chapman,Daniela Rhodes,Douglas R. Higgs +12 more
TL;DR: The unexpected association of a putative transcriptional regulator with highly repetitive DNA provides a potential explanation for the variability in phenotype of patients with identical mutations in the ATRX gene.
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Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting.
Heather M. Marshall,Keshet Ronen,Charles C. Berry,Manuel Llano,Heidi G. Sutherland,Dyana T. Saenz,Wendy A. Bickmore,Eric M. Poeschla,Frederic D. Bushman +8 more
TL;DR: Reductions were seen in lentiviral infectivity compared to controls and the frequency of integration in transcription units was correlated with the cell-type specific levels of PSIP1/LEDGF/p75 expression.