H
Heitor A. Paula Neto
Researcher at Federal University of Rio de Janeiro
Publications - 10
Citations - 342
Heitor A. Paula Neto is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Antibody & In vivo. The author has an hindex of 6, co-authored 10 publications receiving 262 citations. Previous affiliations of Heitor A. Paula Neto include Rio de Janeiro State University & University of São Paulo.
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Journal ArticleDOI
Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation
Sandra Mara A. Arraes,Sandra Mara A. Arraes,Marta S. De Freitas,Marta S. De Freitas,Simone V. da Silva,Simone V. da Silva,Heitor A. Paula Neto,Heitor A. Paula Neto,José C. Alves-Filho,José C. Alves-Filho,Maria Auxiliadora Martins,Maria Auxiliadora Martins,Anibal Basile-Filho,Anibal Basile-Filho,Beatriz Martins Tavares-Murta,Beatriz Martins Tavares-Murta,Christina Barja-Fidalgo,Christina Barja-Fidalgo,Fernando Q. Cunha,Fernando Q. Cunha +19 more
TL;DR: Data suggest that endogenous mediators produced during sepsis might continually activate circulating neutrophils, leading to GRK activation, which may induce neutrophil desensitization to chemoattractants.
Journal ArticleDOI
Zika Virus Infects, Activates, and Crosses Brain Microvascular Endothelial Cells, without Barrier Disruption.
Michelle Premazzi Papa,Lana Monteiro Meuren,Sharton Vinicius Antunes Coelho,Carolina Lucas,Yasmin Mucunã Mustafá,Flavio Lemos Matassoli,Paola P. Silveira,Paula S. Frost,Paula Pezzuto,Milene Rocha Ribeiro,Amilcar Tanuri,Maurício Lacerda Nogueira,Loraine Campanati,Marcelo T. Bozza,Heitor A. Paula Neto,Pedro M. Pimentel-Coelho,Cláudia P. Figueiredo,Renato S. Aguiar,Luciana Barros de Arruda +18 more
TL;DR: The effects of ZIKV replication in human brain microvascular endothelial cells, as an in vitro model of blood brain barrier (BBB), and evaluated virus extravasation and BBB integrity in an in vivo mouse experimental model suggest that ZikV infects and activates endothelial Cells, and might reach the CNS through basolateral release, transcytosis or transinfection processes.
Journal ArticleDOI
Effects of Food Additives on Immune Cells As Contributors to Body Weight Gain and Immune-Mediated Metabolic Dysregulation.
Heitor A. Paula Neto,Priscila Ausina,Lilian S. Gomez,João G. B. Leandro,Patricia Zancan,Mauro Sola-Penna +5 more
TL;DR: Evidence from the literature is reviewed showing that food additives have relevant effects on cells of the immune system that could contribute to immune-mediated metabolic dysregulation, and their use should be taken with caution.
Journal ArticleDOI
Prostaglandin E2 and dexamethasone regulate eosinophil differentiation and survival through a nitric oxide- and CD95-dependent pathway.
Carla P. Jones,Heitor A. Paula Neto,Heitor A. Paula Neto,Jamil Assreuy,B. Boris Vargaftig,Maria Ignez C Gaspar Elsas,P. Xavier Elsas +6 more
TL;DR: PGE2 induces apoptosis in developing eosinophils through inducible NOS, leading to NO-dependent activation of the CD95L/CD95 pathway, while dexamethasone antagonizes the effects of PGE2 on the same targets.
Journal ArticleDOI
Exogenous citrate impairs glucose tolerance and promotes visceral adipose tissue inflammation in mice.
João G. B. Leandro,Jair Machado Espindola-Netto,Maria Carolina F. Vianna,Lilian S. Gomez,Thainá M. Demaria,Monica M. Marinho-Carvalho,Patricia Zancan,Heitor A. Paula Neto,Mauro Sola-Penna +8 more
TL;DR: In this article, the effect of citrate consumption on post-prandial fat production and weight gain was investigated in mice with or without citrate and sucrose, and the results showed that mice receiving citrate or citrate+sucrose did not show increased weight gain or an increase in the weight of the liver, skeletal muscles or adipose tissues.