H
Henri L Saenz
Researcher at University of Basel
Publications - 4
Citations - 335
Henri L Saenz is an academic researcher from University of Basel. The author has contributed to research in topics: Bartonella bacilliformis & Bartonella henselae. The author has an hindex of 4, co-authored 4 publications receiving 317 citations.
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Journal ArticleDOI
Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors
Henri L Saenz,Philipp Engel,Michèle C Stoeckli,Christa Lanz,Günter Raddatz,Muriel Vayssier-Taussat,Muriel Vayssier-Taussat,Richard J. Birtles,Stephan C. Schuster,Stephan C. Schuster,Christoph Dehio +10 more
TL;DR: Comparison and functional genomics are used to infer pathogenicity genes specific to the radiating lineage of Bartonella tribocorum, and it is suggested that these genes may have facilitated adaptation to the host environment.
Journal ArticleDOI
The Trw Type IV Secretion System of Bartonella Mediates Host-Specific Adhesion to Erythrocytes
Muriel Vayssier-Taussat,Danielle Le Rhun,Hong Kuan Deng,Francis Biville,Sandra Cescau,Antoine Danchin,Geneviève Marignac,Evelyne Lenaour,Henri Jean Boulouis,Maria Mavris,Lionel Arnaud,Huanming Yang,Jing Wang,Maxime Québatte,Philipp Engel,Henri L Saenz,Christoph Dehio +16 more
TL;DR: It is shown that the laterally acquired Trw T4SS diversified in the Bartonella lineage to facilitate host-restricted adhesion to erythrocytes in a wide range of mammals.
Journal ArticleDOI
Signature-tagged mutagenesis: technical advances in a negative selection method for virulence gene identification.
Henri L Saenz,Christoph Dehio +1 more
TL;DR: TheSTM method has been developed further owing to recent advances including different designs of the signature-tags and profound changes in the mode of detection, which promoted substantially the application range and versatility of the STM method.