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Henrik B. Rasmussen

Researcher at Copenhagen University Hospital

Publications -  90
Citations -  5250

Henrik B. Rasmussen is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Endogenous retrovirus & Carboxylesterase 1. The author has an hindex of 28, co-authored 90 publications receiving 4515 citations. Previous affiliations of Henrik B. Rasmussen include Roskilde University.

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Journal ArticleDOI

Enantioselective Determination of Methylphenidate and Ritalinic Acid in Whole Blood from Forensic Cases Using Automated Solid-Phase Extraction and Liquid Chromatography–Tandem Mass Spectrometry

Ragnar Thomsen, +2 more
- 01 Oct 2012 - 
TL;DR: In blood from 10 living subjects that were not suspected of being intoxicated by methylphenidate, the concentration ranges and patterns were similar to those of the postmortem cases, and methyl phenidate does not appear to undergo significant postmortem redistribution.
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No influence of the polymorphisms CYP2C19 and CYP2D6 on the efficacy of cyclophosphamide, thalidomide, and bortezomib in patients with Multiple Myeloma

Annette Juul Vangsted, +9 more
- 04 Aug 2010 - 
TL;DR: It is found that in patients who were treated with bortezomib and were carriers of one or two defective CYP2D6 alleles there was a trend towards a better time-to-next treatment, and the potential influence of different polymorphisms in the CYP enzymes on the outcome of treatment was explored.
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Additive effect of the HLA-DR15 haplotype on susceptibility to multiple sclerosis.

Henrik B. Rasmussen, +2 more
- 01 Apr 2001 - 
TL;DR: The results suggested that the effect of the DRB1*1501, DQA1*0102, DQB1*0602 haplotype on the susceptibility to MS is additive, perhaps reflecting that development of the disease is facilitated by a high density surface expression of the antigen presenting molecules encoded by this haplotype.
Journal ArticleDOI

Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics

Henrik B. Rasmussen, +18 more
- 21 Apr 2015 - 
TL;DR: The composition of the gene encoding CES1 is described, variants of this gene are reported with focus upon those with a potential effect on drug metabolism and an overview of the protein structure of this enzyme is provided bringing notice to mechanisms involved in the regulation of enzyme activity.
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Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects

Sheila P. Gregório, +8 more
- 01 Dec 2006 - 
TL;DR: The consistency of this finding in two independent and unrelated populations reinforces the veracity of this association between non-synonymous variants of five genes of the Notch pathway and schizophrenia in a group of Brazilian patients and 200-paired controls.