H
Henrik E. Mei
Researcher at Leibniz Association
Publications - 77
Citations - 7451
Henrik E. Mei is an academic researcher from Leibniz Association. The author has contributed to research in topics: Mass cytometry & Immune system. The author has an hindex of 32, co-authored 70 publications receiving 5115 citations. Previous affiliations of Henrik E. Mei include Humboldt State University & Stanford University.
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Journal ArticleDOI
Tissue Distribution and Dependence of Responsiveness of Human Antigen-Specific Memory B Cells
Claudia Giesecke,Daniela Frölich,Karin Reiter,Henrik E. Mei,Ina Wirries,Rainer Kuhly,Monica Killig,Timor Glatzer,K Stölzel,Carsten Perka,Peter E. Lipsky,Thomas Dörner +11 more
TL;DR: The spleen and tonsil appear to be dispensable to preserve adequate responsiveness to secondary antigenic challenge, and human mBCs recirculate through PB and reside in different lymphoid organs that do not reflect different mBC maturity stages.
Journal ArticleDOI
Correction: Corrigendum: Generation of stable monoclonal antibody–producing B cell receptor–positive human memory B cells by genetic programming
Mark J. Kwakkenbos,Sean A. Diehl,Etsuko Yasuda,Arjen Q. Bakker,Caroline M. M. van Geelen,Michaël V. Lukens,Grada M. van Bleek,Myra N Widjojoatmodjo,Willy M. J. M. Bogers,Henrik E. Mei,Andreas Radbruch,Ferenc A. Scheeren,Hergen Spits,Tim Beaumont +13 more
TL;DR: This work has shown that the retroviral vectors containing BCL-6 and Bcl-xL have been generated by a for-profit company, AIMM Therapeutics, which makes the plasmids available.
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Role of the spleen in peripheral memory B-cell homeostasis in patients with autoimmune thrombocytopenia purpura.
Lorena Martinez-Gamboa,Henrik E. Mei,Christoph Loddenkemper,Boris Ballmer,Arne Hansen,Peter E. Lipsky,Florian Emmerich,Andreas Radbruch,Abdulgabar Salama,Thomas Dörner +9 more
TL;DR: The spleen plays a fundamental role in controlling peripheral memory B cell homeostasis in both AITP and HD and regulates activated CD95+ B cells in patients with AITPs, indicating their enhanced activation status.
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Long-lived plasma cells in immunity and immunopathology.
Katrin Moser,Gwendolin Muehlinghaus,Rudi Manz,Henrik E. Mei,Caroline Voigt,Taketoshi Yoshida,Thomas Dörner,Falk Hiepe,Andreas Radbruch +8 more
TL;DR: In NZB/W mice, a model for systemic lupus, long-lived autoreactive plasma cells are present not only in bone marrow, but also in inflamed tissues and spleen, suggesting that these cells contribute to induction of immunopathology.
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Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy.
Nitya Nair,Henrik E. Mei,Shih-Yu Chen,Matthew Hale,Garry P. Nolan,Holden T. Maecker,Mark C. Genovese,C. Garrison Fathman,Chan C. Whiting +8 more
TL;DR: The capabilities of mass cytometry are outlined and the potential of this technology to enhance the discovery of cellular biomarkers for rheumatoid arthritis, a prototypical autoimmune disease is illustrated.