F
Falk Hiepe
Researcher at Humboldt University of Berlin
Publications - 325
Citations - 18996
Falk Hiepe is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Lupus erythematosus & Antibody. The author has an hindex of 64, co-authored 310 publications receiving 15902 citations. Previous affiliations of Falk Hiepe include University of Tokyo & German Center for Neurodegenerative Diseases.
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Journal ArticleDOI
2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus
Martin Aringer,Karen H. Costenbader,David I. Daikh,Ralph Brinks,Marta Mosca,Rosalind Ramsey-Goldman,Josef S Smolen,David Wofsy,Dimitrios T. Boumpas,Diane L. Kamen,David Jayne,Ricard Cervera,Nathalie Costedoat-Chalumeau,Betty Diamond,Dafna D. Gladman,Bevra H. Hahn,Falk Hiepe,Søren Jacobsen,Dinesh Khanna,Kirsten Lerstrøm,Elena Massarotti,Joseph M. McCune,Guillermo Ruiz-Irastorza,Jorge Sanchez-Guerrero,Matthias Schneider,Murray B. Urowitz,George Bertsias,Bimba F. Hoyer,Nicolai Leuchten,Chiara Tani,Sara K. Tedeschi,Zahi Touma,Gabriela Schmajuk,Branimir Anić,Florence Assan,Tak Mao Chan,Ann E. Clarke,Mary K. Crow,László Czirják,Andrea Doria,Winfried Graninger,Bernadett Halda-Kiss,Sarfaraz Hasni,Peter M. Izmirly,Michelle Jung,Gábor Kumánovics,Xavier Mariette,Ivan Padjen,José M. Pego-Reigosa,Juanita Romero-Diaz,Íñigo Rúa-Figueroa Fernández,Raphaèle Seror,Georg Stummvoll,Yoshiya Tanaka,Maria G Tektonidou,Carlos Vasconcelos,Edward M Vital,Daniel J. Wallace,Sule Yavuz,Pier Luigi Meroni,Marvin J. Fritzler,Ray Naden,Thomas Dörner,Sindhu R. Johnson +63 more
TL;DR: To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism and the American College of Rheumatology (ACR).
Journal ArticleDOI
Competence and competition : the challenge of becoming a long-lived plasma cell
Andreas Radbruch,Gwendolin Muehlinghaus,Elke Luger,Ayako Inamine,Kenneth G. C. Smith,Thomas Dörner,Falk Hiepe +6 more
TL;DR: Studies of the biology of plasma cells reveal a mechanism of intriguing simplicity and elegance that focuses memory provided by plasma cells on recently encountered pathogens while minimizing the 'fading' of memory for pathogens encountered in the distant past.
Journal ArticleDOI
Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis
Gerald B. Appel,Gabriel Contreras,Mary Anne Dooley,Ellen M. Ginzler,David A. Isenberg,David Jayne,Lei Shi Li,Eduardo Mysler,Jorge Sánchez-Guerrero,Neil Solomons,David Wofsy,Carlos Abud,Sharon G. Adler,Graciela S. Alarcón,Elisa N. Albuquerque,Fernando Almeida,Alejandro Alvarellos,Gerald B. Appel,Hilario Avila,Cornelia Blume,Ioannis Boletis,Alain Bonnardeaux,Alan Braun,Jill P. Buyon,Ricard Cervera,Nan Chen,Shun-Le Chen,António Gomes Da Costa,Razeen Davids,David D'Cruz,Enrique de Ramón,Atul Deodhar,Andrea Doria,Bertrand Dussol,Paul Emery,Justus Fiechtner,Jürgen Floege,Hilda Fragoso-Loyo,Richard Furie,Rozina Ghazalli,Cybele Ghossein,Gary S. Gilkeson,EM Ginzler,Caroline Gordon,Jennifer M. Grossman,Jieruo Gu,Loïc Guillevin,Pierre Yves Hatron,Gisela Herrera,Falk Hiepe,Frédéric Houssiau,Osvaldo Hübscher,Claudia Hura,Joshua Kaplan,Gianna Mastroianni Kirsztajn,Emese Kiss,Ghazali Ahmad Kutty,Maurice Laville,Maria Lazaro,Oliver Lenz,Leishi Li,Liz Lightstone,Sam Lim,Michel Malaise,Susan Manzi,Juan Carlos Marcos,Olivier Meyer,Pablo Monge,Saraladev Naicker,Nathaniel Neal,Michael Neuwelt,Kathy Nicholls,Nancy J. Olsen,José Ordi-Ros,Barbara E. Ostrov,Manuel Pestana,Michelle Petri,G. Pokorny,Jacques Pourrat,Jiaqi Qian,Jai Radhakrishnan,Brad H. Rovin,Julio Sanchez Roman,Joseph C. Shanahan,William Shergy,Fotini Skopouli,Alberto Spindler,Christopher Striebich,Robert Sundel,Charles R. Swanepoel,Yen Tan Si,Guillermo Tate,Vladimír Tesaŕ,Mohamed Tikly,Haiyan Wang,Rosnawati Yahya,Xueqing Yu,Fengchun Zhang,Diana Zoruba +98 more
TL;DR: Although most patients in both treatment groups experienced clinical improvement, the study did not meet its primary objective of showing that MMF was superior to IVC as induction treatment for lupus nephritis.
Journal ArticleDOI
2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus
Martin Aringer,Karen H. Costenbader,David I. Daikh,Ralph Brinks,Marta Mosca,Rosalind Ramsey-Goldman,Josef S Smolen,David Wofsy,Dimitrios T. Boumpas,Dimitrios T. Boumpas,Diane L. Kamen,David Jayne,Ricard Cervera,Nathalie Costedoat-Chalumeau,Betty Diamond,Dafna D. Gladman,Bevra H. Hahn,Falk Hiepe,Søren Jacobsen,Dinesh Khanna,Kirsten Lerstrøm,Elena Massarotti,Joseph M. McCune,Guillermo Ruiz-Irastorza,Jorge Sanchez-Guerrero,Matthias Schneider,Murray B. Urowitz,George Bertsias,Bimba F. Hoyer,Nicolai Leuchten,Chiara Tani,Sara K. Tedeschi,Zahi Touma,Gabriela Schmajuk,Branimir Anić,Florence Assan,Tak Mao Chan,Ann E. Clarke,Mary K. Crow,László Czirják,Andrea Doria,Winfried Graninger,Bernadett Halda-Kiss,Sarfaraz Hasni,Peter M. Izmirly,Michelle Jung,Gábor Kumánovics,Xavier Mariette,Ivan Padjen,José M. Pego-Reigosa,Juanita Romero-Diaz,Íñigo Rúa-Figueroa Fernández,Raphaèle Seror,Georg Stummvoll,Yoshiya Tanaka,Maria G Tektonidou,Carlos Vasconcelos,Edward M Vital,Edward M Vital,Daniel J. Wallace,Sule Yavuz,Pier Luigi Meroni,Marvin J. Fritzler,Ray Naden,Thomas Dörner,Sindhu R. Johnson,Sindhu R. Johnson +66 more
TL;DR: These new classification criteria for systemic lupus erythematosus have excellent sensitivity and specificity, and were developed using rigorous methodology with multidisciplinary and international input.
Journal ArticleDOI
Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus.
Marcus Odendahl,A.M. Jacobi,Arne Hansen,Eugen Feist,Falk Hiepe,Gerd R Burmester,Peter E. Lipsky,Andreas Radbruch,Thomas Dörner +8 more
TL;DR: There are profound abnormalities in the various B cell compartments in SLE that respond differently to immunosuppressive therapy, and CD27high plasma cells showed a similar degree of somatic hypermutation, but preferentially employed VH4 family members.