H
Hilda High
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 5
Citations - 1010
Hilda High is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Exome & Mutation (genetic algorithm). The author has an hindex of 4, co-authored 5 publications receiving 720 citations. Previous affiliations of Hilda High include Royal North Shore Hospital.
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Journal ArticleDOI
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.
Vinod P. Balachandran,Marta Łuksza,Julia N. Zhao,Vladimir Makarov,John Alec Moral,Romain Remark,Brian Herbst,Gokce Askan,Umesh Bhanot,Yasin Senbabaoglu,Daniel K. Wells,Charles Ian Ormsby Cary,Olivera Grbovic-Huezo,Marc A. Attiyeh,Benjamin D. Medina,Jennifer Q. Zhang,Jennifer K. Loo,Joseph Saglimbeni,Mohsen Abu-Akeel,Roberta Zappasodi,Nadeem Riaz,Martin Smoragiewicz,Z. Larkin Kelley,Z. Larkin Kelley,Olca Basturk,Amber L. Johns,R. Scott Mead,Anthony J. Gill,David K. Chang,David K. Chang,Skye McKay,Lorraine A. Chantrill,Venessa T. Chin,Angela Chou,Jeremy L. Humphris,Marina Pajic,Angela Steinmann,Mehreen Arshi,Mehreen Arshi,Ali Drury,Danielle Froio,Danielle Froio,Ashleigh Morgan,Paul Timpson,David Hermann,Claire Vennin,Sean C. Warren,Mark Pinese,Jianmin Wu,Andreia V. Pinho,Katherine Tucker,Lesley Andrews,Jaswinder S. Samra,Jennifer Arena,Jennifer Arena,Nick Pavlakis,Hilda High,Anubhav Mittal,Andrew V. Biankin,Peter Bailey,Sancha Martin,Elizabeth A. Musgrove,Marc D. Jones,Marc D. Jones,Craig Nourse,Nigel B. Jamieson,Alina Stoita,David Williams,Allan D. Spigelman,Nicola Waddell,John V. Pearson,Ann-Marie Patch,Katia Nones,Felicity Newell,Pamela Mukhopadhyay,Venkateswar Addala,Stephen H. Kazakoff,Oliver Holmes,Conrad Leonard,Scott Wood,Christina Xu,Sean M. Grimmond,Oliver Hofmann,Peter Wilson,Angelika N. Christ,Timothy J. C. Bruxner,Ray Asghari,Neil D. Merrett,Darren Pavey,Amitabha Das,Annabel Goodwin,Peter H. Cosman,Kasim Ismail,Chelsie O'Connor,Caroline Cooper,Peter Grimison,James G. Kench,Charbel Sandroussi,Vincent Lam,Duncan J. Mcleod,Adnan Nagrial,Judy Kirk,Virginia James,Michael Texler,Cindy Forest,Krishna Epari,Mo Ballal,David R. Fletcher,Sanjay Mukhedkar,Nikolajs Zeps,Maria Beilin,Kynan Feeney,Nan Q. Nguyen,Andrew Ruszkiewicz,Chris Worthley,John W. Chen,Mark Brooke-Smith,Virginia Papangelis,Andrew D. Clouston,P. Martin,Andrew Barbour,Thomas J. O'Rourke,Jonathan Fawcett,Kellee Slater,Michael Hatzifotis,Peter Hodgkinson,Mehrdad Nikfarjam,James R. Eshleman,Ralph H. Hruban,Christopher L. Wolfgang,Mary Hodgin,Aldo Scarpa,Rita T. Lawlor,Stefania Beghelli,Vincenzo Corbo,Maria Scardoni,Claudio Bassi,Mithat Gonen,Arnold J. Levine,Peter J. Allen,Douglas T. Fearon,Douglas T. Fearon,Miriam Merad,Sacha Gnjatic,Christine A. Iacobuzio-Donahue,Jedd D. Wolchok,Ronald P. DeMatteo,Timothy A. Chan,Benjamin Greenbaum,Taha Merghoub,Taha Merghoub,Steven D. Leach +151 more
TL;DR: In this paper, the authors used genetic, immunohistochemical and transcriptional immunoprofiling, computational biophysics, and functional assays to identify T-cell antigens in long-term survivors of pancreatic cancer.
Journal ArticleDOI
Efficacy of Chemotherapy in BRCA1/2 Mutation Carrier Ovarian Cancer in the Setting of PARP Inhibitor Resistance: A Multi-Institutional Study
Joo Ern Ang,Charlie Gourley,C. Bethan Powell,Hilda High,Ronnie Shapira-Frommer,Vincent Castonguay,Jacques De Greve,T. Atkinson,Timothy A. Yap,Shahneen Sandhu,Susana Banerjee,Lee-may Chen,Michael Friedlander,Bella Kaufman,Amit M. Oza,Ursula A. Matulonis,Louise J. Barber,Iwanka Kozarewa,Kerry Fenwick,Ioannis Assiotis,James Campbell,Lina Chen,Johann S. de Bono,Martin Gore,Christopher J. Lord,Alan Ashworth,Stan B. Kaye +26 more
TL;DR: Heavily pretreated patients with BRCA1/2 mutation carrier ovarian cancer who are PARPi-resistant retain the potential to respond to subsequent chemotherapy, including platinum-based agents, according to a retrospective review of PBMCOC.
Journal ArticleDOI
Lost in translation: Returning germline genetic results in genome-scale cancer research
Amber L. Johns,Skye McKay,Jeremy L. Humphris,Mark Pinese,Lorraine A. Chantrill,Lorraine A. Chantrill,R. Scott Mead,R. Scott Mead,Katherine M. Tucker,Lesley Andrews,Annabel Goodwin,Conrad Leonard,Hilda High,Katia Nones,Ann-Marie Patch,Neil D. Merrett,Nick Pavlakis,Karin S. Kassahn,Jaswinder S. Samra,David Miller,David K. Chang,Marina Pajic,John V. Pearson,Sean M. Grimmond,Nicola Waddell,Nikolajs Zeps,Anthony J. Gill,Anthony J. Gill,Andrew V. Biankin +28 more
TL;DR: Using the work of the Australian Pancreatic Cancer Genome Initiative, barriers and opportunities associated with a comprehensive process of RoR in large-scale genomic research are discussed that may be useful for others developing their own policies.
Journal ArticleDOI
Renal Carcinoma Associated With Succinate Dehydrogenase B Mutation: A New and Unique Subtype of Renal Carcinoma
Julie Y. Paik,Christopher W. Toon,Diana E. Benn,Hilda High,Csilla Hasovitz,Nick Pavlakis,Roderick J. Clifton-Bligh,Anthony J. Gill +7 more
Journal ArticleDOI
Use of chemotherapy (CT) in BRCA1/2-deficient ovarian cancer (BDOC) patients (pts) with poly-ADP-ribose polymerase inhibitor (PARPi) resistance: A multi-institutional study.
Joo Ern Ang,Charlie Gourley,Hilda High,Ronnie Shapira-Frommer,C. Bethan Powell,Vincent Castonguay,Jacques De Greve,Timothy A. Yap,Peter C.C. Fong,David Olmos,Susana Banerjee,Lee-may Chen,Michael Friedlander,Bella Kaufman,Amit M. Oza,Johann S. de Bono,Martin Gore,Stanley B. Kaye +17 more
TL;DR: The aim here was to re-examine this issue in a larger multi-institutional population, and provide the first clinical data relating to the use of post-PARPi CT in BDOC.