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Claire Vennin
Researcher at Garvan Institute of Medical Research
Publications - 25
Citations - 1706
Claire Vennin is an academic researcher from Garvan Institute of Medical Research. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 13, co-authored 20 publications receiving 1214 citations. Previous affiliations of Claire Vennin include Netherlands Cancer Institute.
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Journal ArticleDOI
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.
Vinod P. Balachandran,Marta Łuksza,Julia N. Zhao,Vladimir Makarov,John Alec Moral,Romain Remark,Brian Herbst,Gokce Askan,Umesh Bhanot,Yasin Senbabaoglu,Daniel K. Wells,Charles Ian Ormsby Cary,Olivera Grbovic-Huezo,Marc A. Attiyeh,Benjamin D. Medina,Jennifer Q. Zhang,Jennifer K. Loo,Joseph Saglimbeni,Mohsen Abu-Akeel,Roberta Zappasodi,Nadeem Riaz,Martin Smoragiewicz,Z. Larkin Kelley,Z. Larkin Kelley,Olca Basturk,Amber L. Johns,R. Scott Mead,Anthony J. Gill,David K. Chang,David K. Chang,Skye McKay,Lorraine A. Chantrill,Venessa T. Chin,Angela Chou,Jeremy L. Humphris,Marina Pajic,Angela Steinmann,Mehreen Arshi,Mehreen Arshi,Ali Drury,Danielle Froio,Danielle Froio,Ashleigh Morgan,Paul Timpson,David Hermann,Claire Vennin,Sean C. Warren,Mark Pinese,Jianmin Wu,Andreia V. Pinho,Katherine Tucker,Lesley Andrews,Jaswinder S. Samra,Jennifer Arena,Jennifer Arena,Nick Pavlakis,Hilda High,Anubhav Mittal,Andrew V. Biankin,Peter Bailey,Sancha Martin,Elizabeth A. Musgrove,Marc D. Jones,Marc D. Jones,Craig Nourse,Nigel B. Jamieson,Alina Stoita,David Williams,Allan D. Spigelman,Nicola Waddell,John V. Pearson,Ann-Marie Patch,Katia Nones,Felicity Newell,Pamela Mukhopadhyay,Venkateswar Addala,Stephen H. Kazakoff,Oliver Holmes,Conrad Leonard,Scott Wood,Christina Xu,Sean M. Grimmond,Oliver Hofmann,Peter Wilson,Angelika N. Christ,Timothy J. C. Bruxner,Ray Asghari,Neil D. Merrett,Darren Pavey,Amitabha Das,Annabel Goodwin,Peter H. Cosman,Kasim Ismail,Chelsie O'Connor,Caroline Cooper,Peter Grimison,James G. Kench,Charbel Sandroussi,Vincent Lam,Duncan J. Mcleod,Adnan Nagrial,Judy Kirk,Virginia James,Michael Texler,Cindy Forest,Krishna Epari,Mo Ballal,David R. Fletcher,Sanjay Mukhedkar,Nikolajs Zeps,Maria Beilin,Kynan Feeney,Nan Q. Nguyen,Andrew Ruszkiewicz,Chris Worthley,John W. Chen,Mark Brooke-Smith,Virginia Papangelis,Andrew D. Clouston,P. Martin,Andrew Barbour,Thomas J. O'Rourke,Jonathan Fawcett,Kellee Slater,Michael Hatzifotis,Peter Hodgkinson,Mehrdad Nikfarjam,James R. Eshleman,Ralph H. Hruban,Christopher L. Wolfgang,Mary Hodgin,Aldo Scarpa,Rita T. Lawlor,Stefania Beghelli,Vincenzo Corbo,Maria Scardoni,Claudio Bassi,Mithat Gonen,Arnold J. Levine,Peter J. Allen,Douglas T. Fearon,Douglas T. Fearon,Miriam Merad,Sacha Gnjatic,Christine A. Iacobuzio-Donahue,Jedd D. Wolchok,Ronald P. DeMatteo,Timothy A. Chan,Benjamin Greenbaum,Taha Merghoub,Taha Merghoub,Steven D. Leach +151 more
TL;DR: In this paper, the authors used genetic, immunohistochemical and transcriptional immunoprofiling, computational biophysics, and functional assays to identify T-cell antigens in long-term survivors of pancreatic cancer.
Journal ArticleDOI
Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer
Claire Vennin,Kendelle J. Murphy,Kendelle J. Murphy,Jennifer P. Morton,Thomas R. Cox,Thomas R. Cox,Marina Pajic,Marina Pajic,Paul Timpson,Paul Timpson +9 more
TL;DR: Relationships between the pancreatic tumor extracellular matrix, the vasculature, the immune system, and metabolism, are described and the implications for the development of stromal compartment-specific therapies are discussed.
Journal ArticleDOI
Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment
David Herrmann,James R.W. Conway,Claire Vennin,Astrid Magenau,William E. Hughes,Jennifer P. Morton,Paul Timpson +6 more
TL;DR: The current advantages and challenges of employing 3D systems in the study of cancer and an overview to guide the appropriate use of distinct models in cancer research are highlighted.
Journal ArticleDOI
Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer
Angela Chou,Danielle Froio,Adnan Nagrial,Adnan Nagrial,Ashleigh Parkin,Kendelle J. Murphy,Venessa T. Chin,Dalia Wohl,Angela Steinmann,Rhys Stark,Alison Drury,Stacey N. Walters,Claire Vennin,Andrew Burgess,Andrew Burgess,Mark Pinese,Lorraine A. Chantrill,Lorraine A. Chantrill,Mark J. Cowley,Timothy J. Molloy,Nicola Waddell,Amber L. Johns,Sean M. Grimmond,David K. Chang,Andrew V. Biankin,Owen J. Sansom,Jennifer P. Morton,Shane T. Grey,Shane T. Grey,Thomas R. Cox,John Turchini,Jaswinder S. Samra,Stephen Clarke,Paul Timpson,Paul Timpson,Anthony J. Gill,Marina Pajic,Marina Pajic +37 more
TL;DR: Subtype-specific in vivo efficacy of PD-0332991-based therapy was for the first time observed at multiple stages of PDA progression: primary tumour growth, recurrence (second-line therapy) and metastatic setting and may potentially be guided by a simple biomarker (RB protein).
Journal ArticleDOI
A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts
Max Nobis,David Herrmann,Sean C. Warren,Shereen Kadir,Wilfred Leung,Monica J. Killen,Astrid Magenau,David A. Stevenson,Morghan C. Lucas,Nadine Reischmann,Claire Vennin,James R.W. Conway,Alice Boulghourjian,Anaiis Zaratzian,Andrew M. K. Law,David Gallego-Ortega,Christopher J. Ormandy,Stacey N. Walters,Shane T. Grey,Jacqueline Bailey,Tatyana Chtanova,Julian M. W. Quinn,Paul A. Baldock,Peter I. Croucher,Juliane P. Schwarz,Agata Mrowinska,Lei Zhang,Herbert Herzog,Andrius Masedunskas,Edna C. Hardeman,Peter W. Gunning,Gonzalo del Monte-Nieto,Gonzalo del Monte-Nieto,Richard P. Harvey,Richard P. Harvey,Michael S. Samuel,Marina Pajic,Ewan J. McGhee,Anna-Karin E. Johnsson,Owen J. Sansom,Heidi C.E. Welch,Jennifer P. Morton,Douglas Strathdee,Kurt I. Anderson,Paul Timpson +44 more
TL;DR: The generation of a RhoA-fluorescence resonance energy transfer (FRET) biosensor mouse and its utility for monitoring real-time activity of RhoA in a variety of native tissues in vivo in real time are described.