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Skye McKay
Researcher at Garvan Institute of Medical Research
Publications - 12
Citations - 1685
Skye McKay is an academic researcher from Garvan Institute of Medical Research. The author has contributed to research in topics: Cancer & Pancreatic cancer. The author has an hindex of 4, co-authored 9 publications receiving 1196 citations. Previous affiliations of Skye McKay include Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.
Vinod P. Balachandran,Marta Łuksza,Julia N. Zhao,Vladimir Makarov,John Alec Moral,Romain Remark,Brian Herbst,Gokce Askan,Umesh Bhanot,Yasin Senbabaoglu,Daniel K. Wells,Charles Ian Ormsby Cary,Olivera Grbovic-Huezo,Marc A. Attiyeh,Benjamin D. Medina,Jennifer Q. Zhang,Jennifer K. Loo,Joseph Saglimbeni,Mohsen Abu-Akeel,Roberta Zappasodi,Nadeem Riaz,Martin Smoragiewicz,Z. Larkin Kelley,Z. Larkin Kelley,Olca Basturk,Amber L. Johns,R. Scott Mead,Anthony J. Gill,David K. Chang,David K. Chang,Skye McKay,Lorraine A. Chantrill,Venessa T. Chin,Angela Chou,Jeremy L. Humphris,Marina Pajic,Angela Steinmann,Mehreen Arshi,Mehreen Arshi,Ali Drury,Danielle Froio,Danielle Froio,Ashleigh Morgan,Paul Timpson,David Hermann,Claire Vennin,Sean C. Warren,Mark Pinese,Jianmin Wu,Andreia V. Pinho,Katherine Tucker,Lesley Andrews,Jaswinder S. Samra,Jennifer Arena,Jennifer Arena,Nick Pavlakis,Hilda High,Anubhav Mittal,Andrew V. Biankin,Peter Bailey,Sancha Martin,Elizabeth A. Musgrove,Marc D. Jones,Marc D. Jones,Craig Nourse,Nigel B. Jamieson,Alina Stoita,David Williams,Allan D. Spigelman,Nicola Waddell,John V. Pearson,Ann-Marie Patch,Katia Nones,Felicity Newell,Pamela Mukhopadhyay,Venkateswar Addala,Stephen H. Kazakoff,Oliver Holmes,Conrad Leonard,Scott Wood,Christina Xu,Sean M. Grimmond,Oliver Hofmann,Peter Wilson,Angelika N. Christ,Timothy J. C. Bruxner,Ray Asghari,Neil D. Merrett,Darren Pavey,Amitabha Das,Annabel Goodwin,Peter H. Cosman,Kasim Ismail,Chelsie O'Connor,Caroline Cooper,Peter Grimison,James G. Kench,Charbel Sandroussi,Vincent Lam,Duncan J. Mcleod,Adnan Nagrial,Judy Kirk,Virginia James,Michael Texler,Cindy Forest,Krishna Epari,Mo Ballal,David R. Fletcher,Sanjay Mukhedkar,Nikolajs Zeps,Maria Beilin,Kynan Feeney,Nan Q. Nguyen,Andrew Ruszkiewicz,Chris Worthley,John W. Chen,Mark Brooke-Smith,Virginia Papangelis,Andrew D. Clouston,P. Martin,Andrew Barbour,Thomas J. O'Rourke,Jonathan Fawcett,Kellee Slater,Michael Hatzifotis,Peter Hodgkinson,Mehrdad Nikfarjam,James R. Eshleman,Ralph H. Hruban,Christopher L. Wolfgang,Mary Hodgin,Aldo Scarpa,Rita T. Lawlor,Stefania Beghelli,Vincenzo Corbo,Maria Scardoni,Claudio Bassi,Mithat Gonen,Arnold J. Levine,Peter J. Allen,Douglas T. Fearon,Douglas T. Fearon,Miriam Merad,Sacha Gnjatic,Christine A. Iacobuzio-Donahue,Jedd D. Wolchok,Ronald P. DeMatteo,Timothy A. Chan,Benjamin Greenbaum,Taha Merghoub,Taha Merghoub,Steven D. Leach +151 more
TL;DR: In this paper, the authors used genetic, immunohistochemical and transcriptional immunoprofiling, computational biophysics, and functional assays to identify T-cell antigens in long-term survivors of pancreatic cancer.
Journal ArticleDOI
Whole-genome landscape of pancreatic neuroendocrine tumours
Aldo Scarpa,David K. Chang,Katia Nones,Katia Nones,Vincenzo Corbo,Ann-Marie Patch,Ann-Marie Patch,Peter Bailey,Peter Bailey,Rita T. Lawlor,Amber L. Johns,David Miller,Andrea Mafficini,Borislav Rusev,Maria Scardoni,Davide Antonello,Stefano Barbi,Katarzyna O. Sikora,Sara Cingarlini,Caterina Vicentini,Skye McKay,Michael C.J. Quinn,Michael C.J. Quinn,Timothy J. C. Bruxner,Angelika N. Christ,Ivon Harliwong,Senel Idrisoglu,Suzanne McLean,Craig Nourse,Craig Nourse,Ehsan Nourbakhsh,Peter J. Wilson,Matthew J. Anderson,J. Lynn Fink,Felicity Newell,Felicity Newell,Nick Waddell,Oliver Holmes,Oliver Holmes,Stephen H. Kazakoff,Stephen H. Kazakoff,Conrad Leonard,Conrad Leonard,Scott Wood,Scott Wood,Qinying Xu,Qinying Xu,Shivashankar H. Nagaraj,Eliana Amato,Irene Dalai,Samantha Bersani,Ivana Cataldo,Angelo Paolo Dei Tos,Paola Capelli,Maria Vittoria Davì,Luca Landoni,Anna Malpaga,Marco Miotto,Vicki L. J. Whitehall,Vicki L. J. Whitehall,Barbara A. Leggett,Barbara A. Leggett,Barbara A. Leggett,Janelle L. Harris,Jonathan M. Harris,Marc D. Jones,Jeremy L. Humphris,Lorraine A. Chantrill,Venessa T. Chin,Adnan Nagrial,Marina Pajic,Christopher J. Scarlett,Christopher J. Scarlett,Andreia V. Pinho,Ilse Rooman,Christopher W. Toon,Jianmin Wu,Jianmin Wu,Mark Pinese,Mark J. Cowley,Andrew Barbour,Amanda Mawson,Emily S. Humphrey,Emily K. Colvin,Angela Chou,Angela Chou,Jessica A. Lovell,Nigel B. Jamieson,Nigel B. Jamieson,Fraser Duthie,Marie-Claude Gingras,Marie-Claude Gingras,William E. Fisher,Rebecca A. Dagg,Loretta Lau,Michael Lee,Hilda A. Pickett,Roger R. Reddel,Jaswinder S. Samra,Jaswinder S. Samra,James G. Kench,James G. Kench,James G. Kench,Neil D. Merrett,Neil D. Merrett,Krishna Epari,Nam Q. Nguyen,Nikolajs Zeps,Nikolajs Zeps,Massimo Falconi,Michele Simbolo,Giovanni Butturini,George Van Buren,Stefano Partelli,Matteo Fassan,Kum Kum Khanna,Anthony J. Gill,Anthony J. Gill,David A. Wheeler,Richard A. Gibbs,Elizabeth A. Musgrove,Claudio Bassi,Giampaolo Tortora,Paolo Pederzoli,John V. Pearson,John V. Pearson,Nicola Waddell,Nicola Waddell,Andrew V. Biankin,Sean M. Grimmond +129 more
TL;DR: In this paper, the authors performed whole-genome sequencing of 102 primary pancreatic neuroendocrine tumours and defined the genomic events that characterize their pathogenesis, including a deficiency in G:C,>T:A base excision repair due to inactivation of MUTYH, which encodes a DNA glycosylase.
Journal ArticleDOI
Hypermutation In Pancreatic Cancer
Jeremy L. Humphris,Ann-Marie Patch,Ann-Marie Patch,Katia Nones,Katia Nones,Peter Bailey,Peter Bailey,Amber L. Johns,Skye McKay,David K. Chang,David Miller,David Miller,Marina Pajic,Marina Pajic,Karin S. Kassahn,Karin S. Kassahn,Michael C.J. Quinn,Michael C.J. Quinn,Timothy J. C. Bruxner,Angelika N. Christ,Ivon Harliwong,Senel Idrisoglu,Suzanne Manning,Craig Nourse,Craig Nourse,Ehsan Nourbakhsh,Andrew Stone,Peter J. Wilson,Matthew J. Anderson,J. Lynn Fink,Oliver Holmes,Oliver Holmes,Stephen H. Kazakoff,Stephen H. Kazakoff,Conrad Leonard,Conrad Leonard,Felicity Newell,Felicity Newell,Nick Waddell,Scott Wood,Scott Wood,Ronald S Mead,Qinying Xu,Qinying Xu,Jianmin Wu,Mark Pinese,Mark J. Cowley,Mark J. Cowley,Marc D. Jones,Marc D. Jones,Adnan Nagrial,Venessa T. Chin,Lorraine A. Chantrill,Lorraine A. Chantrill,Amanda Mawson,Angela Chou,Angela Chou,Christopher J. Scarlett,Christopher J. Scarlett,Andreia V. Pinho,Ilse Rooman,Marc Giry-Laterriere,Jaswinder S. Samra,Jaswinder S. Samra,James G. Kench,James G. Kench,James G. Kench,Neil D. Merrett,Christopher W. Toon,Krishna Epari,Nam Q. Nguyen,Andrew Barbour,Nikolajs Zeps,Nigel B. Jamieson,Nigel B. Jamieson,Colin J. McKay,C. Ross Carter,Euan J. Dickson,Janet Graham,Janet Graham,Fraser Duthie,Karin A. Oien,Jane Hair,Jennifer P. Morton,Owen J. Sansom,Robert Grützmann,Ralph H. Hruban,Anirban Maitra,Christine A. Iacobuzio-Donahue,Richard D. Schulick,Christopher L. Wolfgang,Richard A. Morgan,Rita T. Lawlor,Borislav Rusev,Vincenzo Corbo,Roberto Salvia,Ivana Cataldo,Giampaolo Tortora,Margaret A. Tempero,Oliver Hofmann,James R. Eshleman,Christian Pilarsky,Aldo Scarpa,Elizabeth A. Musgrove,Elizabeth A. Musgrove,Elizabeth A. Musgrove,Anthony J. Gill,Anthony J. Gill,Anthony J. Gill,John V. Pearson,John V. Pearson,Sean M. Grimmond,Sean M. Grimmond,Nicola Waddell,Nicola Waddell,Andrew V. Biankin +115 more
TL;DR: Defining mutation load in individual pancreatic cancers and the optimal assay for patient selection may inform clinical trial design for immunotherapy in pancreatic cancer.
Journal ArticleDOI
Lost in translation: Returning germline genetic results in genome-scale cancer research
Amber L. Johns,Skye McKay,Jeremy L. Humphris,Mark Pinese,Lorraine A. Chantrill,Lorraine A. Chantrill,R. Scott Mead,R. Scott Mead,Katherine M. Tucker,Lesley Andrews,Annabel Goodwin,Conrad Leonard,Hilda High,Katia Nones,Ann-Marie Patch,Neil D. Merrett,Nick Pavlakis,Karin S. Kassahn,Jaswinder S. Samra,David Miller,David K. Chang,Marina Pajic,John V. Pearson,Sean M. Grimmond,Nicola Waddell,Nikolajs Zeps,Anthony J. Gill,Anthony J. Gill,Andrew V. Biankin +28 more
TL;DR: Using the work of the Australian Pancreatic Cancer Genome Initiative, barriers and opportunities associated with a comprehensive process of RoR in large-scale genomic research are discussed that may be useful for others developing their own policies.
Journal ArticleDOI
Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours
Aldo Scarpa,David K. Chang,Katia Nones,Vincenzo Corbo,Ann-Marie Patch,Peter Bailey,Rita T. Lawlor,Amber L. Johns,David Miller,Andrea Mafficini,Borislav Rusev,Maria Scardoni,Davide Antonello,Stefano Barbi,Katarzyna O. Sikora,Sara Cingarlini,Caterina Vicentini,Skye McKay,Michael C.J. Quinn,Timothy J. C. Bruxner,Angelika N. Christ,Ivon Harliwong,Senel Idrisoglu,Suzanne McLean,Craig Nourse,Ehsan Nourbakhsh,Peter Wilson,Matthew J. Anderson,J. Lynn Fink,Felicity Newell,Nick Waddell,Oliver Holmes,Stephen H. Kazakoff,Conrad Leonard,Scott Wood,Qinying Xu,Shivashankar H. Nagaraj,Eliana Amato,Irene Dalai,Samantha Bersani,Ivana Cataldo,Angelo Paolo Dei Tos,Paola Capelli,Maria Vittoria Davì,Luca Landoni,Anna Malpaga,Marco Miotto,Vicki L. J. Whitehall,Barbara A. Leggett,Janelle L. Harris,Jonathan M. Harris,Marc D. Jones,Jeremy L. Humphris,Lorraine A. Chantrill,Venessa T. Chin,Adnan Nagrial,Marina Pajic,Christopher J. Scarlett,Andreia V. Pinho,Ilse Rooman,Christopher W. Toon,Jianmin Wu,Mark Pinese,Mark J. Cowley,Andrew B. Barbour,Amanda Mawson,Emily S. Humphrey,Emily K. Colvin,Angela Chou,Jessica A. Lovell,Nigel B. Jamieson,Fraser Duthie,Marie-Claude Gingras,William E. Fisher,Rebecca A. Dagg,Loretta Lau,Michael Lee,Hilda A. Pickett,Roger R. Reddel,Jaswinder S. Samra,James G. Kench,Neil D. Merrett,Krishna Epari,Nam Q. Nguyen,Nikolajs Zeps,Massimo Falconi,Michele Simbolo,Giovanni Butturini,George Van Buren,Stefano Partelli,Matteo Fassan,Kum Kum Khanna,Anthony J. Gill,David A. Wheeler,Richard A. Gibbs,Elizabeth A. Musgrove,Claudio Bassi,Giampaolo Tortora,Paolo Pederzoli,John V. Pearson,Nicola Waddell,Andrew V. Biankin,Sean M. Grimmond +102 more
TL;DR: This corrects the article to show that the method used to derive the H2O2 “spatially aggregating force” is based on a two-step process, not a single step, like in the previous version of this paper.