H
Hindrik Mulder
Researcher at Lund University
Publications - 167
Citations - 11481
Hindrik Mulder is an academic researcher from Lund University. The author has contributed to research in topics: Insulin & Islet. The author has an hindex of 54, co-authored 158 publications receiving 10047 citations. Previous affiliations of Hindrik Mulder include University of Texas at Dallas & University of Texas Southwestern Medical Center.
Papers
More filters
Journal ArticleDOI
Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables
Emma Ahlqvist,Petter Storm,Annemari Käräjämäki,Mats Martinell,Mozhgan Dorkhan,Annelie Carlsson,Petter Vikman,Rashmi B. Prasad,Dina Mansour Aly,Peter Almgren,Ylva Wessman,Nael Shaat,Peter Spégel,Hindrik Mulder,Eero Lindholm,Olle Melander,Ola Hansson,Ulf Malmqvist,Åke Lernmark,Kaj Lahti,Tom Forsén,Tiinamaija Tuomi,Tiinamaija Tuomi,Anders Rosengren,Anders Rosengren,Leif Groop,Leif Groop +26 more
TL;DR: Five replicable clusters of patients with diabetes were identified, which had significantly different patient characteristics and risk of diabetic complications, which might eventually help to tailor and target early treatment to patients who would benefit most.
Journal ArticleDOI
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.
Hans E. Hohmeier,Hindrik Mulder,Guoxun Chen,Rosemarie Henkel-Rieger,Marc Prentki,Christopher B. Newgard +5 more
TL;DR: It is concluded that clonal selection of INS-1 cells allows isolation of cell lines that exhibit markedly enhanced and stable responsiveness to glucose and several of its known potentiators, which may be attractive new vehicles for studies of beta-cell function.
Journal ArticleDOI
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.
Valeriya Lyssenko,Cecilia Nagorny,Michael R. Erdos,Nils Wierup,Anna Jonsson,Peter Spégel,Marco Bugliani,Richa Saxena,Richa Saxena,Malin Fex,Nicolo Pulizzi,Bo Isomaa,Tiinamaija Tuomi,Peter M. Nilsson,Johanna Kuusisto,Jaakko Tuomilehto,Michael Boehnke,David Altshuler,David Altshuler,Frank Sundler,Johan G. Eriksson,Anne U. Jackson,Markku Laakso,Piero Marchetti,Richard M. Watanabe,Hindrik Mulder,Leif Groop,Leif Groop +27 more
TL;DR: In this paper, the authors showed that the risk genotype of this SNP predicts future type 2 diabetes (T2D) in two large prospective studies, and the risk was associated with impairment of early insulin response to both oral and intravenous glucose and with faster deterioration of insulin secretion over time.
Journal ArticleDOI
The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas
TL;DR: Ghrelin is expressed in a quite prominent endocrine cell population in human fetal pancreas, and ghrelin expression in the Pancreas precedes by far that in the stomach.
Journal ArticleDOI
Orexin loss in Huntington's disease
Åsa Petersén,Joana Gil,Marion L.C. Maat-Schieman,Maria Björkqvist,Heikki Tanila,Inês M. Araújo,Ruben Smith,Natalija Popovic,Nils Wierup,Per Norlén,Jia-Yi Li,Raymund A.C. Roos,Frank Sundler,Hindrik Mulder,Patrik Brundin +14 more
TL;DR: The results show that the loss of orexin is a novel and potentially very important pathology in HD and could be used as a biomarker reflecting neurodegeneration.