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Piero Marchetti

Researcher at University of Pisa

Publications -  583
Citations -  33471

Piero Marchetti is an academic researcher from University of Pisa. The author has contributed to research in topics: Insulin & Pancreatic islets. The author has an hindex of 82, co-authored 549 publications receiving 28654 citations. Previous affiliations of Piero Marchetti include Sapienza University of Rome & University of Genoa.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

Valeriya Lyssenko, +15 more
- 01 Aug 2007 - 
TL;DR: The increased risk of T2D conferred by variants in TCF7L2 involves the enteroinsular axis, enhanced expression of the gene in islets, and impaired insulin secretion.
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Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.

Valeriya Lyssenko, +27 more
- 01 Jan 2009 - 
TL;DR: In this paper, the authors showed that the risk genotype of this SNP predicts future type 2 diabetes (T2D) in two large prospective studies, and the risk was associated with impairment of early insulin response to both oral and intravenous glucose and with faster deterioration of insulin secretion over time.
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Prolonged Exposure to Free Fatty Acids Has Cytostatic and Pro-Apoptotic Effects on Human Pancreatic Islets: Evidence that β-Cell Death Is Caspase Mediated, Partially Dependent on Ceramide Pathway, and Bcl-2 Regulated

Roberto Lupi, +14 more
- 01 May 2002 - 
TL;DR: Extended exposure to FFAs has cytostatic and pro-apoptotic effects on human pancreatic beta-cells, likely to be due to the FFA-induced reduction of intraislet glucose metabolism, and the proapoptosis effects are mostly caspase mediated, partially dependent on ceramide pathway, and possibly Bcl-2 regulated.
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New-onset diabetes after transplantation: 2003 International consensus guidelines. Proceedings of an international expert panel meeting. Barcelona, Spain, 19 February 2003

Jaime A. Davidson, +13 more
- 27 May 2003 -