H
Hiroaki Sasai
Researcher at Osaka University
Publications - 293
Citations - 9623
Hiroaki Sasai is an academic researcher from Osaka University. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 50, co-authored 278 publications receiving 9019 citations. Previous affiliations of Hiroaki Sasai include University of Burgundy & University of Tokyo.
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Enantioselective and aerobic oxidative coupling of 2-naphthol derivatives using chiral dinuclear vanadium(V) complex in water
TL;DR: In this paper, the enantioselective oxidative coupling of 2-naphthols in water was established using dinuclear vanadium(V/IV) catalysis with O2 as the sole co-oxidant.
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Enantioselective Aza-Wacker-Type Cyclization Promoted by Pd-SPRIX Catalyst.
TL;DR: An enantioselective aza-Wacker-type reaction was developed that attacked intramolecularly by the nitrogen nucleophile to construct several heterocycles such as morpholines, piperazines, pipers, and their benzo-fused derivatives in up to 88% yield with up to 80% ee.
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Stereocontrolled syntheses of phorbol analogs and evaluation of their binding affinity to PKC
TL;DR: Stereocontrolled syntheses of a series of phorbol analogs, and evaluation of their potential to bind to the signal transduction enzyme protein kinase C (PKC) are described.
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An enantioselective organocatalyzed aza-Morita–Baylis–Hillman reaction of isatin-derived ketimines with acrolein
TL;DR: The present protocol readily furnished (S) or (R)-aza-MBH adducts with a chiral tetrasubstituted carbon stereogenic center in up to 98% ee.
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Pd(II)-SPRIX catalyzed enantioselective construction of pyrrolizines/pyrroloindoles employing molecular oxygen as the sole oxidant
TL;DR: Pd(II)-SPRIX catalyst coupled with an environmentally benign molecular oxygen as the sole oxidant successfully exploited the construction of pyrrolizines/pyrroloindoles, imperative scaffolds of bio-potent molecules through intramolecular C-N and C-C bond forming reactions in good yields with appreciable enantioselectivities.