H
Hirokazu Tanaka
Researcher at Japan Advanced Institute of Science and Technology
Publications - 166
Citations - 3804
Hirokazu Tanaka is an academic researcher from Japan Advanced Institute of Science and Technology. The author has contributed to research in topics: Motor control & Liver transplantation. The author has an hindex of 31, co-authored 165 publications receiving 3415 citations. Previous affiliations of Hirokazu Tanaka include Columbia University & Salk Institute for Biological Studies.
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In vitro activities of a new lipopeptide antifungal agent, FK463, against a variety of clinically important fungi.
Shuichi Tawara,Fumiaki Ikeda,Katsuyuki Maki,Yoshihiko Morishita,Kazumi Otomo,Noriko Teratani,Toshio Goto,Masaki Tomishima,Hidenori Ohki,Akira Yamada,Koji Kawabata,Hisashi Takasugi,Kazuo Sakane,Hirokazu Tanaka,Fumio Matsumoto,Shogo Kuwahara +15 more
TL;DR: Results from preclinical in vitro evaluations performed thus far indicate that FK463 should be a potent parenteral antifungal agent.
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Adaptation to Visuomotor Rotation Through Interaction Between Posterior Parietal and Motor Cortical Areas
TL;DR: It is proposed that rotation adaptation proceeds through changes in synaptic weights between neurons in posterior parietal cortex and motor cortex driven by a prediction error computed by the cerebellum.
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An optimization principle for determining movement duration.
TL;DR: It is suggested that one aspect of movement planning, as revealed by movement duration, may be to assign an endpoint accuracy criterion for a given task and context.
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FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. II. Structure determination.
Nobuharu Shigematsu,Hirotsugu Ueda,Shigehiro Takase,Hirokazu Tanaka,Kyoko Yamamoto,Toshuiji Tada +5 more
TL;DR: The structure of FR901228 (C 24 H 36 N 4 O 6 S 2 ), including stereochemical details, was determined by a combination of spectroscopic, chemical evidence and single-crystal X-ray crystallographic analysis using anomalous dispersion from the S atoms.
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Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure
Kenji Takemoto,Etsuro Hatano,Keiko Iwaisako,Masatoshi Takeiri,Naruto Noma,Saori Ohmae,Kan Toriguchi,Kazutaka Tanabe,Hirokazu Tanaka,Satoru Seo,Kojiro Taura,Keigo Machida,Norihiko Takeda,Shigehira Saji,Shinji Uemoto,Masataka Asagiri +15 more
TL;DR: It is shown that RIPK1 phosphorylation, which is a hallmark of RIPK‐dependent necrosis, was induced by APAP, and the expression pattern in the liver overlapped with that of CYP2E1, whose activity around the central vein area has been demonstrated to be critical for the development of APAP‐induced hepatic injury.