Ho-Geun Yoon

TL;DR: These magnetism-engineered iron oxide (MEIO) nanoprobes, when conjugated with antibodies, showed enhanced magnetic resonance imaging (MRI) sensitivity for the detection of cancer markers compared with probes currently available and could enhance the ability to visualize other biological events critical to diagnostics and therapeutics.

TL;DR: The purification and functional characterization of the human N‐CoR complex is reported and the roles of HDAC3 and TBL/TBLR1 are revealed and evidence for the functional importance of histone interaction in repression mediated by SMRT–N‐ CoR complexes is provided.

TL;DR: It is demonstrated that Kaiso, a methyl CpG binding protein belonging to the BTB/POZ family of transcription factors, is a component of the human N-CoR complex and revealed the mechanism by which it represses transcription.

TL;DR: In this paper, epigallocatechin-3-gallate (EGCG) was identified as a histone acetyltransferase inhibitor (HATi) with global specificity for the majority of HAT enzymes but with no activity toward epigenetic enzymes including HDAC, SIRT1, and HMTase.

TL;DR: A novel protocol for the preparation of MMPNs and characterization to evaluate the sensitivity and stability of prepared nanohybrids is reported and targeted detection ability by MRI and synergistic tumoricidal efficacy on breast cancer cells were investigated for cellular and animal models.