Ho Tsoi

TL;DR: Analysis of the microbial communities in human gut mucosae at different stages of colorectal tumorigenesis suggests that a taxonomically defined microbial consortium is implicated in the development of CRC.

TL;DR: Evidence is provided that the fecal microbiota from patients with CRC can promote tumorigenesis in germ-free mice and mice given a carcinogen, and up-regulation of genes involved in cell proliferation, stemness, apoptosis, angiogenesis, invasiveness, and metastasis are revealed in mice fed with stool from Patients with CRC.

TL;DR: Levels of P anaerobius are increased in human colon tumor tissues and adenomas compared with non-tumor tissues; this bacteria increases colon dysplasia in a mouse model of CRC.

TL;DR: CA4 methylation may serve as an independent biomarker for the recurrence of CRC through the inhibition of the Wnt signalling pathway by targeting the WTAP–WT1–TBL1 axis.

TL;DR: miR-139-5p plays a pivotal role in colon cancer through inhibiting cell proliferation, metastasis, and promoting apoptosis and cell cycle arrest by targeting oncogenic NOTCH1.