H
Hong Wei
Researcher at Third Military Medical University
Publications - 129
Citations - 6846
Hong Wei is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Gut flora & Medicine. The author has an hindex of 29, co-authored 101 publications receiving 4250 citations. Previous affiliations of Hong Wei include Shanghai Jiao Tong University & Huazhong Agricultural University.
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Journal ArticleDOI
Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes
Liping Zhao,Liping Zhao,Feng Zhang,Xiaoying Ding,Guojun Wu,Yan Y. Lam,Xuejiao Wang,Huaqing Fu,Xinhe Xue,Chunhua Lu,Jilin Ma,Lihua Yu,Chengmei Xu,Zhongying Ren,Ying Xu,Songmei Xu,Hongli Shen,Xiuli Zhu,Yu Shi,Qingyun Shen,Weiping Dong,Rui Liu,Yunxia Ling,Yue Zeng,Xing-peng Wang,Qianpeng Zhang,Jing Wang,Linghua Wang,Yanqiu Wu,Benhua Zeng,Hong Wei,Menghui Zhang,Yongde Peng,Chenhong Zhang +33 more
TL;DR: It is found that adopting a high-fiber diet promoted the growth of SCFA-producing organisms in diabetic humans and had better improvement in hemoglobin A1c levels, partly via increased glucagon-like peptide-1 production.
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Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9.
Dong Niu,Hong-Jiang Wei,Lin Lin,Haydy George,Tao Wang,I-Hsiu Lee,Hong-Ye Zhao,Yong Wang,Yinan Kan,Ellen Shrock,Emal Lesha,Gang Wang,Yonglun Luo,Yubo Qing,Deling Jiao,Heng Zhao,Xiaoyang Zhou,Shouqi Wang,Hong Wei,Marc Güell,George M. Church,George M. Church,Luhan Yang +22 more
TL;DR: The value ofPERV inactivation to prevent cross-species viral transmission is highlighted and the successful production of PERV-inactivated animals to address the safety concern in clinical xenotransplantation are demonstrated.
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Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice
Sunny H. Wong,Liuyang Zhao,Xiang Zhang,Geicho Nakatsu,Juqiang Han,Weiqi Xu,Xue Xiao,Thomas N.Y. Kwong,Ho Tsoi,William K.K. Wu,Benhua Zeng,Francis K.L. Chan,Joseph J.Y. Sung,Hong Wei,Jun Yu +14 more
TL;DR: Evidence is provided that the fecal microbiota from patients with CRC can promote tumorigenesis in germ-free mice and mice given a carcinogen, and up-regulation of genes involved in cell proliferation, stemness, apoptosis, angiogenesis, invasiveness, and metastasis are revealed in mice fed with stool from Patients with CRC.
Journal ArticleDOI
The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice
Peng Zheng,Benhua Zeng,Meiling Liu,Jianjun Chen,Junxi Pan,Yu Han,Yiyun Liu,Ke Cheng,Chanjuan Zhou,Haiyang Wang,Xinyu Zhou,Siwen Gui,Seth W. Perry,Ma-Li Wong,Julio Licinio,Hong Wei,Peng Xie +16 more
TL;DR: It is found that unmedicated and medicated patients with SCZ had a decreased microbiome α-diversity index and marked disturbances of gut microbial composition versus healthy controls (HCs), and the SCZ microbiome itself can alter neurochemistry and neurologic function in ways that may be relevant to SCZ pathology.
Journal ArticleDOI
Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children
Chenhong Zhang,Aihua Yin,Hongde Li,R.Z. Wang,Guojun Wu,Jian Shen,Menghui Zhang,Linghua Wang,Yaping Hou,Haimei Ouyang,Yan Zhang,Yi-Nan Zheng,Jicheng Wang,Xiaofei Lv,Yulan Wang,Feng Zhang,Benhua Zeng,Wenxia Li,Feiyan Yan,Yufeng Zhao,Xiaoyan Pang,Xiaojun Zhang,Huaqing Fu,Feng Chen,Naisi Zhao,Bruce R. Hamaker,Bruce R. Hamaker,Laura C. Bridgewater,Laura C. Bridgewater,David Weinkove,Karine Clément,Joël Doré,Elaine Holmes,Huasheng Xiao,Guoping Zhao,Shengli Yang,Peer Bork,Jeremy K. Nicholson,Hong Wei,Huiru Tang,Xiaozhuang Zhang,Liping Zhao +41 more
TL;DR: It is found that children genetically obese with Prader–Willi syndrome shared a similar dysbiosis in their gut microbiota with those having diet-related obesity, which contributes to the alleviation of metabolic deteriorations in obesity regardless of the primary driving forces.