H
Holly M. Biggs
Researcher at Duke University
Publications - 23
Citations - 1524
Holly M. Biggs is an academic researcher from Duke University. The author has contributed to research in topics: Leptospirosis & Population. The author has an hindex of 14, co-authored 23 publications receiving 1198 citations.
Papers
More filters
Journal ArticleDOI
Evaluation of In-Hospital Management for Febrile Illness in Northern Tanzania before and after 2010 World Health Organization Guidelines for the Treatment of Malaria
Andrew M. Moon,Holly M. Biggs,Matthew P. Rubach,John A. Crump,Venace P. Maro,Venace P. Maro,Wilbrod Saganda,Elizabeth A. Reddy +7 more
TL;DR: Differences in historic and recent hospital cohorts in the diagnosis and treatment of febrile illness in a low malaria prevalence area of northern Tanzania are assessed to assess changes in the treatment of malaria and bacterial infections.
Journal ArticleDOI
Incidence of invasive salmonella disease in sub-Saharan Africa: a multicentre population-based surveillance study
Florian Marks,Vera von Kalckreuth,Peter Aaby,Yaw Adu-Sarkodie,Muna Ahmed El Tayeb,Mohammad Ali,Abraham Aseffa,Stephen Baker,Holly M. Biggs,Morten Bjerregaard-Andersen,Robert F. Breiman,Robert F. Breiman,James Campbell,Leonard Cosmas,John A. Crump,Ligia Maria Cruz Espinoza,Jessica Fung Deerin,Denise Dekker,Barry S. Fields,Nagla Gasmelseed,Julian T. Hertz,Nguyen Van Minh Hoang,Justin Im,Anna Jaeger,Hyon Jin Jeon,Leon Parfait Kabore,Karen H. Keddy,Frank Konings,Ralf Krumkamp,Benedikt Ley,Benedikt Ley,Sandra Valborg Løfberg,Jürgen May,Christian Meyer,Christian Meyer,Eric D. Mintz,Joel M. Montgomery,Aissatou Ahmet Niang,Chelsea Nichols,Beatrice Olack,Gi Deok Pak,Ursula Panzner,Jin Kyung Park,Se Eun Park,Henintsoa Rabezanahary,Raphaël Rakotozandrindrainy,Tiana Mirana Raminosoa,Tsiriniaina Jean Luco Razafindrabe,Emmanuel Sampo,Heidi Schütt-Gerowitt,Heidi Schütt-Gerowitt,Amy Gassama Sow,Nimako Sarpong,Hye Jin Seo,Arvinda Sooka,Abdramane Bassiahi Soura,Adama Tall,Mekonnen Teferi,Kamala Thriemer,Kamala Thriemer,Michelle R. Warren,Biruk Yeshitela,John D. Clemens,John D. Clemens,Thomas F. Wierzba +64 more
TL;DR: The development of iNTS vaccines and the introduction of S Typhi conjugate vaccines should be considered for high-incidence settings, such as those identified in this study.
Journal ArticleDOI
Epidemiology of Leptospirosis in Africa: a systematic review of a neglected zoonosis and a paradigm for 'One Health' in Africa
Kathryn J. Allan,Holly M. Biggs,Jo E. B. Halliday,Rudovick Kazwala,Venance P. Maro,Sarah Cleaveland,John A. Crump +6 more
TL;DR: A ‘One Health’ approach is advocated to promote multidisciplinary research efforts to improve understanding of the animal to human transmission of leptospirosis on the African continent.
Journal ArticleDOI
The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa.
Se Eun Park,Se Eun Park,Duy Thanh Pham,Christine J. Boinett,Vanessa K. Wong,Gi Deok Pak,Ursula Panzner,Ligia Maria Cruz Espinoza,Vera von Kalckreuth,Justin Im,Heidi Schütt-Gerowitt,Heidi Schütt-Gerowitt,John A. Crump,Robert F. Breiman,Robert F. Breiman,Yaw Adu-Sarkodie,Ellis Owusu-Dabo,Raphaël Rakotozandrindrainy,Abdramane Bassiahi Soura,Abraham Aseffa,Nagla Gasmelseed,Karen H. Keddy,Jürgen May,Amy Gassama Sow,Amy Gassama Sow,Peter Aaby,Peter Aaby,Holly M. Biggs,Julian T. Hertz,Joel M. Montgomery,Leonard Cosmas,Beatrice Olack,Barry S. Fields,Nimako Sarpong,Tsiriniaina Jean Luco Razafindrabe,Tiana Mirana Raminosoa,Leon Parfait Kabore,Emmanuel Sampo,Mekonnen Teferi,Biruk Yeshitela,Muna Ahmed El Tayeb,Arvinda Sooka,Christian Meyer,Christian Meyer,Ralf Krumkamp,Denise Dekker,Anna Jaeger,Sven Poppert,Adama Tall,Aissatou Ahmet Niang,Morten Bjerregaard-Andersen,Morten Bjerregaard-Andersen,Sandra Valborg Løfberg,Sandra Valborg Løfberg,Hye Jin Seo,Hyon Jin Jeon,Jessica Fung Deerin,Jin Kyung Park,Frank Konings,Mohammad Ali,Mohammad Ali,John D. Clemens,John D. Clemens,John D. Clemens,Peter Hughes,Juliet Nsimire Sendagala,Tobias Vudriko,Robert Downing,Usman N. Ikumapayi,Grant A. Mackenzie,Stephen K. Obaro,Stephen K. Obaro,Stephen K. Obaro,Silvia Argimón,David M. Aanensen,Andrew J. Page,Jacqueline A. Keane,Sebastián Duchêne,Zoe A. Dyson,Kathryn E. Holt,Gordon Dougan,Florian Marks,Florian Marks,Stephen Baker,Stephen Baker +84 more
TL;DR: A phylogenetic reconstruction of whole genome sequenced 249 contemporaneous S. Typhi isolates from 11 sub-Saharan African countries is presented, identifying genes and plasmids associated with antibiotic resistance and showing that multi-drug resistance is highly pervasive inSub-Saharan Africa.
Journal ArticleDOI
Invasive Salmonella Infections in Areas of High and Low Malaria Transmission Intensity in Tanzania
Holly M. Biggs,Rebecca Lester,Behzad Nadjm,Behzad Nadjm,George Mtove,Jim Todd,Grace D. Kinabo,Rune Philemon,Ben Amos,Anne B. Morrissey,Hugh Reyburn,Hugh Reyburn,John A. Crump +12 more
TL;DR: Where malaria transmission was intense, invasive NTS was common and Salmonella Typhi was uncommon, whereas the inverse was observed at a low malaria transmission site and the relationship between these pathogens, the environment, and the host is a compelling area for further research.