H
Hong-Erh Liang
Researcher at University of California, San Francisco
Publications - 42
Citations - 10281
Hong-Erh Liang is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Innate lymphoid cell & Immune system. The author has an hindex of 28, co-authored 38 publications receiving 8525 citations.
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Journal ArticleDOI
Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
Davina Wu,Ari B. Molofsky,Hong-Erh Liang,Roberto R. Ricardo-Gonzalez,Hani A. Jouihan,Jennifer K. Bando,Ajay Chawla,Richard M. Locksley +7 more
TL;DR: It is shown that eosinophils are the major IL-4–expressing cells in white adipose tissues of mice, and, in their absence, AAMs are greatly attenuated.
Journal ArticleDOI
Systemically dispersed innate IL-13-expressing cells in type 2 immunity.
April E. Price,Hong-Erh Liang,Brandon M. Sullivan,R. Lee Reinhardt,Chris J. Eisley,David J. Erle,Richard M. Locksley +6 more
TL;DR: In this paper, lineage-negative IL-25 and IL-33 responsive cells are found to be widely distributed in tissues of the mouse and are particularly prevalent in mesenteric lymph nodes, spleen, and liver.
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Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit
TL;DR: It is shown that tuft cells constitutively express IL-25 to sustain ILC2 homeostasis in the resting lamina propria in mice, and comprise a response circuit that mediates epithelial remodelling associated with type 2 immunity in the small intestine, and perhaps at other mucosal barriers populated by these cells.
Journal ArticleDOI
Type 2 innate lymphoid cells control eosinophil homeostasis
Jesse C. Nussbaum,Steven J. Van Dyken,Jakob von Moltke,Laurence E. Cheng,Alexander Mohapatra,Ari B. Molofsky,Emily E. Thornton,Matthew F. Krummel,Ajay Chawla,Hong-Erh Liang,Richard M. Locksley +10 more
TL;DR: It is shown that serum IL-5 levels are maintained by long-lived type 2 innate lymphoid cells (ILC2) resident in peripheral tissues, and this dissociated regulation can be tuned by nutrient intake and central circadian rhythms.
Journal ArticleDOI
Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages
Ari B. Molofsky,Jesse C. Nussbaum,Hong-Erh Liang,Steven J. Van Dyken,Laurence E. Cheng,Alexander Mohapatra,Ajay Chawla,Richard M. Locksley +7 more
TL;DR: Innate lymphoid type 2 cells maintain eosinophils and alternatively activated macrophages in visceral fat via the production of IL-5 and IL-13.