H
Hongjun Li
Researcher at Zhejiang University
Publications - 177
Citations - 6180
Hongjun Li is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 29, co-authored 134 publications receiving 4005 citations. Previous affiliations of Hongjun Li include University of Science and Technology of China & Nanjing University.
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Journal ArticleDOI
In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
Qian Chen,Qian Chen,Chao Wang,Xudong Zhang,Guojun Chen,Quanyin Hu,Quanyin Hu,Hongjun Li,Jinqiang Wang,Di Wen,Yuqi Zhang,Yifei Lu,Yifei Lu,Guang Yang,Chen Jiang,Jun Wang,Gianpietro Dotti,Zhen Gu +17 more
TL;DR: The findings indicate that the immunotherapeutic fibrin gel ‘awakens’ the host innate and adaptive immune systems to inhibit both local tumour recurrence post surgery and potential metastatic spread.
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Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy
Hongjun Li,Jin-Zhi Du,Xiao-Jiao Du,Cong-Fei Xu,Chun Yang Sun,Hong-Xia Wang,Zhi Ting Cao,Xianzhu Yang,Yan Hua Zhu,Shuming Nie,Jun Wang +10 more
TL;DR: A stimuli-responsive clustered nanoparticle (iCluster) was developed and justified that its adaptive alterations of physicochemical properties in accordance with the endogenous stimuli of the tumor microenvironment made possible the ultimate overcoming of these barriers, especially the bottleneck of tumor penetration.
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Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration.
Hongjun Li,Jin-Zhi Du,Jing Liu,Xiao-Jiao Du,Song Shen,Yan Hua Zhu,Xiaoyan Wang,Xiaodong Ye,Shuming Nie,Jun Wang +9 more
TL;DR: Comparison studies of pH-sensitive and insensitive nanostructures with similar size, surface charge, and chemical composition in both multicellular spheroids and poorly permeable BxPC-3 pancreatic tumor models demonstrate that the pH-triggered size switching is a viable strategy for improving drug penetration and therapeutic efficacy.
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Thermal conductivity enhancement dependent pH and chemical surfactant for Cu-H2O nanofluids
TL;DR: In this article, the effect of pH and sodium dodecylbenzenesulfonate (SDBS) surfactant on thermal conductivity of nanofluids was measured by a Hot Disk Thermal Constants Anlyser.
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Tumor Acidity-Sensitive Polymeric Vector for Active Targeted siRNA Delivery.
Chun-Yang Sun,Song Shen,Cong-Fei Xu,Hongjun Li,Yang Liu,Zhi-Ting Cao,Xianzhu Yang,Jin-Xing Xia,Jun Wang +8 more
TL;DR: Dm-NP achieved both prolonged circulation and effective accumulation in tumor cells and resulted in the safe and enhanced inhibition of non-small cell lung cancer growth.