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Hongjun Li

Researcher at Zhejiang University

Publications -  177
Citations -  6180

Hongjun Li is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 29, co-authored 134 publications receiving 4005 citations. Previous affiliations of Hongjun Li include University of Science and Technology of China & Nanjing University.

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Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

TL;DR: A stimuli-responsive clustered nanoparticle (iCluster) was developed and justified that its adaptive alterations of physicochemical properties in accordance with the endogenous stimuli of the tumor microenvironment made possible the ultimate overcoming of these barriers, especially the bottleneck of tumor penetration.
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Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration.

TL;DR: Comparison studies of pH-sensitive and insensitive nanostructures with similar size, surface charge, and chemical composition in both multicellular spheroids and poorly permeable BxPC-3 pancreatic tumor models demonstrate that the pH-triggered size switching is a viable strategy for improving drug penetration and therapeutic efficacy.
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Thermal conductivity enhancement dependent pH and chemical surfactant for Cu-H2O nanofluids

TL;DR: In this article, the effect of pH and sodium dodecylbenzenesulfonate (SDBS) surfactant on thermal conductivity of nanofluids was measured by a Hot Disk Thermal Constants Anlyser.
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Tumor Acidity-Sensitive Polymeric Vector for Active Targeted siRNA Delivery.

TL;DR: Dm-NP achieved both prolonged circulation and effective accumulation in tumor cells and resulted in the safe and enhanced inhibition of non-small cell lung cancer growth.