I
Ian R. Poxton
Researcher at University of Edinburgh
Publications - 132
Citations - 6133
Ian R. Poxton is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Clostridium difficile & Antigen. The author has an hindex of 40, co-authored 132 publications receiving 5877 citations.
Papers
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Journal ArticleDOI
Structure and function of lipopolysaccharides
TL;DR: The lipopolysaccharides of Gram-negative bacteria have a profound effect on the mammalian immune system and are of great significance in the pathophysiology of many disease processes.
Journal ArticleDOI
Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008.
Ed J. Kuijper,Frédéric Barbut,Jon S. Brazier,Niels Kleinkauf,Tim Eckmanns,M L Lambert,D. Drudy,Fidelma Fitzpatrick,Camilla Wiuff,Derek J. Brown,J. E. Coia,Hanna Pituch,Paul Reichert,J. Even,Joël Mossong,Andreas F. Widmer,Katharina E. P. Olsen,Franz Allerberger,Daan W. Notermans,Michel Delmée,Bruno Coignard,Mark H. Wilcox,Bhupendra C. Patel,Reno Frei,Elisabeth Nagy,Emilio Bouza,M Marin,T Akerlund,A Virolainen-Julkunen,O. Lyytikäinen,Saara Kotila,A Ingebretsen,B. Smyth,P Rooney,Ian R. Poxton,Dominique L Monnet +35 more
TL;DR: Ongoing epidemiological surveillance of cases of CDI, with periodic characterisation of the strains involved, is required to detect clustering of cases in time and space and to monitor the emergence of new, highly virulent clones.
Journal ArticleDOI
Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates
TL;DR: Ooing epidemiological surveillance of cases of C. difficile-associated diarrhoea, with periodic characterisation of the strains involved, is required to detect clustering of cases in time and space and to monitor the emergence of specific highly virulent clones.
Journal ArticleDOI
Extensive DNA inversions in the B. fragilis genome control variable gene expression
Ana Cerdeño-Tárraga,Sheila Patrick,Lisa Crossman,Garry W. Blakely,Val Abratt,Nicola Lennard,Ian R. Poxton,Brian I. Duerden,Barbara Harris,Michael A. Quail,Andrew R. Barron,Louise Clark,Craig Corton,Jonathan Doggett,Matthew T. G. Holden,Natasha Larke,Alexandra Line,Angela Lord,Halina Norbertczak,Doug Ormond,Claire E. Price,Ester Rabbinowitsch,John Woodward,Bart Barrell,Julian Parkhill +24 more
TL;DR: The complete genome sequence has revealed an unusual breadth of DNA inversion events that potentially control expression of many different components, including surface and secreted components, regulatory molecules, and restriction-modification proteins.
Book
Molecular medical microbiology
TL;DR: Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource, an invaluable reference source of medical bacteriology.