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Ie Ming Shih
Researcher at Johns Hopkins University
Publications - 401
Citations - 40438
Ie Ming Shih is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Ovarian cancer & Serous fluid. The author has an hindex of 97, co-authored 378 publications receiving 35329 citations. Previous affiliations of Ie Ming Shih include Howard Hughes Medical Institute & MedStar Washington Hospital Center.
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Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1.
Jin-Gyoung Jung,Ie Ming Shih,Joon Tae Park,Emily Gerry,Tae Hoen Kim,Ayse Ayhan,Ayse Ayhan,Karen Handschuh,Ben Davidson,Ben Davidson,Amanda N. Fader,Licia Selleri,Tian Li Wang +12 more
TL;DR: An essential role of the stem cell reprogramming factor, PBX1, in mediating chemoresistance in ovarian carcinomas is reported and a mechanistic rationale to target thePBX1/STAT3 axis to antagonize a key mechanism of chemores resistance in ovarian cancers and possibly other human cancers is offered.
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Pathogenesis of ovarian cancer: clues from selected overexpressed genes
Ie Ming Shih,Ben Davidson +1 more
TL;DR: This review focuses on summarizing those exemplified genes that have been demonstrated to have biological functions in promoting ovarian cancer development and potential clinical significance and the views on the limitations and challenges of current ovarian cancer research.
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Molecular genetic analysis of ovarian serous cystadenomas.
Eric J. Cheng,Robert J. Kurman,Menglin Wang,Robert J. Oldt,Brant G. Wang,David M. Berman,Ie Ming Shih +6 more
TL;DR: It appears that serous cystadenomas develop as a hyperplastic expansion from epithelial inclusions with a clonal/neoplastic transformation occurring in a subset of them, and that most serous Cystadenoma are polyclonal.
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Comparison of candidate serologic markers for type I and type II ovarian cancer.
Dan Lu,Elisabetta Kuhn,Robert E. Bristow,Robert L. Giuntoli,Susanne K. Kjaer,Ie Ming Shih,Richard B. S. Roden +6 more
TL;DR: In this paper, the authors examined the value of individual and combinations of ovarian cancer associated blood biomarkers for the discrimination between plasma of patients with type I or II ovarian cancer and disease-free volunteers.
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The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1.
Jim Jinn-Chyuan Sheu,Jung Hye Choi,Isil Yildiz,Fuu Jen Tsai,Yosef Shaul,Tian Li Wang,Ie Ming Shih +6 more
TL;DR: Interaction between Rsf-1 and hSNF2H may define a survival signal in those tumors overexpressing Rs f-1, according to coimmunoprecipitation and in vitro competition tests.