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Ie Ming Shih
Researcher at Johns Hopkins University
Publications - 401
Citations - 40438
Ie Ming Shih is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Ovarian cancer & Serous fluid. The author has an hindex of 97, co-authored 378 publications receiving 35329 citations. Previous affiliations of Ie Ming Shih include Howard Hughes Medical Institute & MedStar Washington Hospital Center.
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Proteomic Analysis of Temporally Stimulated Ovarian Cancer Cells for Biomarker Discovery
TL;DR: LAMP-1 is a promising biomarker for studies of the progression of EGF-stimulated ovarian cancers and might be useful in predicting treatment responses involving tyrosine kinase inhibitors or EGF receptor monoclonal antibodies.
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Discovery of a cell: reflections on the checkered history of intermediate trophoblast and update on its nature and pathologic manifestations.
Robert J. Kurman,Ie Ming Shih +1 more
TL;DR: The initial description of “trophoblastic pseudotumor” opened a new area of research which brought to bear immunohistochemical and molecular genetic analyses that eventually has led to new insights in the diverse morphologic changes occurring in early placentation and also led to the development of a new classification of trophoblastic tumors and tumor-like lesions.
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Loss of NAC1 Expression Is Associated with Defective Bony Patterning in the Murine Vertebral Axis
Kai Lee Yap,Polina Sysa-Shah,Brad Bolon,Ren-Chin Wu,Min Gao,Alice L. Herlinger,Alice L. Herlinger,Fengying Wang,Francesco Faiola,David L. Huso,Kathleen L. Gabrielson,Tian Li Wang,Jianlong Wang,Ie Ming Shih +13 more
TL;DR: Data suggest that NAC1 participates in the motility and differentiation of developing chondrocytes and cartilaginous tissues, and its expression is necessary to maintain normal axial patterning of murine skeleton.
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Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway
Yu Yu,Yohan Suryo Rahmanto,Meng-Horng Lee,Pei Hsun Wu,Jude M. Phillip,Chuan Hsiang Huang,Michele Vitolo,Stephanie Gaillard,Stuart S. Martin,Denis Wirtz,Ie Ming Shih,Tian Li Wang +11 more
TL;DR: It is reported that active recombinant SYK directly phosphorylates cortactin and cofilin, which are critically involved in assembly and dynamics of actin filament through phosphorylation signaling, and is suggested to prevent or suppress the advancement of ovarian malignancies.