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Ie Ming Shih
Researcher at Johns Hopkins University
Publications - 401
Citations - 40438
Ie Ming Shih is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Ovarian cancer & Serous fluid. The author has an hindex of 97, co-authored 378 publications receiving 35329 citations. Previous affiliations of Ie Ming Shih include Howard Hughes Medical Institute & MedStar Washington Hospital Center.
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Journal ArticleDOI
HLA-G immunoreactivity is specific for intermediate trophoblast in gestational trophoblastic disease and can serve as a useful marker in differential diagnosis.
TL;DR: HLA-G immunoreactivity appears to be specific for IT in gestational trophoblastic disease and can serve as a useful marker in the differential diagnosis of these lesions.
Journal Article
Identifying tumor origin using a gene expression-based classification map.
Phillip Buckhaults,Zhen Zhang,Yu Chi Chen,Tian Li Wang,Brad St. Croix,Saurabh Saha,Alberto Bardelli,Patrice J. Morin,Kornelia Polyak,Ralph H. Hruban,Victor E. Velculescu,Ie Ming Shih +11 more
TL;DR: A classification map diagnostic of tumor types was generated based on expression patterns of five genes selected from the SAGE database, providing a reliable and practical approach to determine tumor type in cases of metastatic carcinoma of clinically unknown origin.
Journal ArticleDOI
Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.
Yu Yu,Stephanie Gaillard,Jude M. Phillip,Tai-Chung Huang,Sneha M. Pinto,Nayara G. Tessarollo,Nayara G. Tessarollo,Zhen Zhang,Akhilesh Pandey,Denis Wirtz,Ayse Ayhan,Ayse Ayhan,Ben Davidson,Ben Davidson,Tian Li Wang,Ie Ming Shih +15 more
TL;DR: It is reported that recurrent ovarian carcinomas after paclitaxel/carboplatin treatment have higher levels of spleen tyrosine kinase (SYK) and phospho-SYK, and targeting SYK pathway is a promising strategy to enhance pac litaxel response.
Journal ArticleDOI
Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity.
Tian Li Wang,Morris Ling,Ie Ming Shih,Pham T,Sara I. Pai,Lu Z,Robert J. Kurman,Drew M. Pardoll,Tzyy Choou Wu +8 more
TL;DR: Among the three different routes of DC-E7 vaccine administration in a murine model, it is found that intramuscular administration generated the greatest anti-tumor immunity compared with subcutaneous and intravenous routes of administration.
Journal ArticleDOI
Placental site nodule and characterization of distinctive types of intermediate trophoblast
Ie Ming Shih,Ie Ming Shih,Jeffrey D. Seidman,Jeffrey D. Seidman,Robert J. Kurman,Robert J. Kurman +5 more
TL;DR: There appear to be three subpopulations of IT cells with distinctive morphological and immunohistochemical features that resemble trophoblastic cells in placental site nodules, which contrast with the IT cells in the implantation site that are designated "implantation site IT cells".