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ILKe Nalbantoglu
Researcher at Yale University
Publications - 45
Citations - 1797
ILKe Nalbantoglu is an academic researcher from Yale University. The author has contributed to research in topics: Colitis & Steatosis. The author has an hindex of 18, co-authored 41 publications receiving 1435 citations. Previous affiliations of ILKe Nalbantoglu include Washington University in St. Louis & University of Washington.
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Journal ArticleDOI
Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice
Frederic A. Carvalho,Frederic A. Carvalho,Frederic A. Carvalho,Omry Koren,Julia K. Goodrich,Malin E. V. Johansson,ILKe Nalbantoglu,Jesse D. Aitken,Yueju Su,Benoit Chassaing,William A. Walters,Antonio Gonzalez,Jose C. Clemente,Tyler C. Cullender,Nicolas Barnich,Arlette Darfeuille-Michaud,Matam Vijay-Kumar,Rob Knight,Rob Knight,Ruth E. Ley,Andrew T. Gewirtz +20 more
TL;DR: An innate immune deficiency can result in unstable gut microbiota associated with low-grade inflammation, and harboring proteobacteria can drive and/or instigate chronic colitis.
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Role of liver biopsy in nonalcoholic fatty liver disease.
TL;DR: This review focuses on the specific histologic lesions of NAFLD and NASH, grading and staging, differential diagnoses to be considered, and the continuing role of the liver biopsy in this important liver disease.
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Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges
Frederic A. Carvalho,ILKe Nalbantoglu,Jesse D. Aitken,Robin Uchiyama,Yueju Su,Gregory H. Doho,Matam Vijay-Kumar,Andrew T. Gewirtz,Andrew T. Gewirtz +8 more
TL;DR: Despite not being involved in rapid intestinal gene remodeling upon detection of flagellin, NLRC4-mediated inflammasome activation results in production of IL-1β and IL-18, two cytokines that protect mice from mucosal and systemic challenges.
Journal ArticleDOI
Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis
Kyle S. McCommis,Wesley T. Hodges,Elizabeth M. Brunt,ILKe Nalbantoglu,William G. McDonald,Christopher L. Holley,Hideji Fujiwara,Jean E. Schaffer,Jerry R. Colca,Brian N. Finck +9 more
TL;DR: It is found that MSDC‐0602 prevented and reversed liver fibrosis and suppressed expression of markers of stellate cell activation in livers of mice fed a diet rich in trans‐fatty acids, fructose, and cholesterol.
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Differentiation of Hepatocellular Carcinoma from Other Hepatic Malignancies in Patients at Risk: Diagnostic Performance of the Liver Imaging Reporting and Data System Version 2014
Tyler J. Fraum,Richard Tsai,Eric Rohe,Daniel R. Ludwig,Amber Salter,ILKe Nalbantoglu,Jay P. Heiken,Kathryn J. Fowler +7 more
TL;DR: Modification of the algorithmic role of tumor in vein and rim arterial phase hyperenhancement improves the diagnostic performance of LI-RADS version 2014 in differentiating HCC from non-HCC malignancy.