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Iris E. C. Sommer
Researcher at University Medical Center Groningen
Publications - 454
Citations - 20580
Iris E. C. Sommer is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Schizophrenia & Medicine. The author has an hindex of 68, co-authored 394 publications receiving 16545 citations. Previous affiliations of Iris E. C. Sommer include University of Toronto & University of Michigan.
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Journal ArticleDOI
Effect of optic nerve transection upon myelin protein gene expression by oligodendrocytes: evidence for axonal influences on gene expression.
K. McPhilemy,L. S. Mitchell,Ian R. Griffiths,S. Morrison,A. W. Deary,Iris E. C. Sommer,Peter G. E. Kennedy +6 more
TL;DR: The results show that optic nerve transection has significant effects on myelin protein mRNA expression in oligodendrocytes of optic nerve, however, the changes in myelinprotein gene activity are relatively small and more protracted than those seen in Schwann cells after peripheral nerve section.
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Aberrant resting-state connectivity in non-psychotic individuals with auditory hallucinations
Kelly M. J. Diederen,S. F. W. Neggers,A. D. de Weijer,R. van Lutterveld,Kirstin Daalman,Simon B. Eickhoff,Mareike Clos,René S. Kahn,Iris E. C. Sommer +8 more
TL;DR: Aberrant connectivity of frontal, parahippocampal and superior temporal brain areas can be specifically related to the predisposition to hallucinate in the auditory domain.
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Language disturbances in schizophrenia: the relation with antipsychotic medication.
TL;DR: Several language disturbances were more related to drug type and dose, than to other psychotic symptoms, suggesting that language disturbances may be aggravated by high D2R antipsychotics.
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Evolutionary modifications in human brain connectivity associated with schizophrenia
Martijn P. van den Heuvel,Lianne H. Scholtens,Siemon C. de Lange,Rory Pijnenburg,Weipke Cahn,Neeltje E.M. van Haren,Neeltje E.M. van Haren,Iris E. C. Sommer,Iris E. C. Sommer,Marco Bozzali,Kathrin Koch,Kathrin Koch,Marco P. Boks,Jonathan Repple,Michela Pievani,Longchuan Li,Todd M. Preuss,James K. Rilling +17 more
TL;DR: By comparing the human and chimpanzee connectomes, van den Heuvel et al. demonstrate that connections unique to the human brain show greater involvement in schizophrenia pathology.
Journal ArticleDOI
Do mood symptoms subdivide the schizophrenia phenotype? Association of the GMP6A gene with a depression subgroup.
Marco P. Boks,M. Hoogendoorn,Bart J. Jungerius,Steven C. Bakker,Iris E. C. Sommer,Richard J. Sinke,Roel A. Ophoff,Roel A. Ophoff,René S. Kahn +8 more
TL;DR: Findings could suggest that GMP6A plays a role in the stress‐induced hippocampal alterations that are found in psychiatric disorders in general and schizophrenia in particular.