Iris E. C. Sommer

TL;DR: A genome-wide association meta-analysis of brain MRI data from 35,660 individuals with replication in 15,578 individuals found significant enrichment for loci influencing total surface area within regulatory elements active during prenatal cortical development, supporting the radial unit hypothesis.

TL;DR: The absence of significant linkage argues against the presence of a major gene coding for both traits; rather, the results are suggestive of these traits being two independent polygenic complex traits.

TL;DR: Cortical thickness in the pars orbitalis, paracentral lobule, fusiform gyrus and inferior temporal gyrus was lowest in patients, intermediate in the non-clinical hallucinating group, and highest in control subjects, suggestive of a similar, but milder underlying pathophysiology in this group compared to the psychosis group.

TL;DR: In this paper, the authors used the resources of the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to examine age-related trajectories inferred from cross-sectional measures of the ventricles, the basal ganglia (caudate, putamen, pallidum, and nucleus accumbens), the thalamus, hippocampus and amygdala using magnetic resonance imaging data obtained from 18,605 individuals aged 3-90 years.

TL;DR: An examination of the validity and reliability of the English version of a new assessment, the Questionnaire for Psychotic Experiences (QPE), confirmed that the QPE had good psychometric properties and could be put forward as an accepted measure of the transdiagnostic evaluation of psychotic experiences.