Itamar Kanter

TL;DR: It is shown that the genome has highly constrained dynamics, and suggested that the molecular regulation of chromatin diffusion by lamin A in the nuclear interior is critical for the maintenance of genome organization.

TL;DR: Correlating β-catenin nuclear dynamics to cyclin D1 transcriptional activation showed that the nuclear accumulation rate of change of the signaling factor, and not actual protein levels, correlated with the transcriptional output of the pathway.

TL;DR: This review will survey emerging technologies for single cell transcriptomics, and describe how they are used to study complex disease such as cancer, as well as other biological phenomena such as tissue regeneration, embryonic development, and immune response.

TL;DR: This work demonstrates a sequential map that links human kidney development and tumorigenesis and indicates negative selection for CD133 is required for defining NCAM1+ nephron stem cells in normal and malignant nephrogenesis.

TL;DR: A brief review of recent developments in single-cell technology is provided to provide a quick background for newcomers to the field as well as a deeper description of some of the leading technologies to date.