I
Ivo Lieberam
Researcher at King's College London
Publications - 29
Citations - 3387
Ivo Lieberam is an academic researcher from King's College London. The author has contributed to research in topics: Medicine & Neural stem cell. The author has an hindex of 15, co-authored 20 publications receiving 3126 citations. Previous affiliations of Ivo Lieberam include Howard Hughes Medical Institute & University of Cologne.
Papers
More filters
Journal ArticleDOI
Directed Differentiation of Embryonic Stem Cells into Motor Neurons
TL;DR: It is shown that developmentally relevant signaling factors can induce mouse embryonic stem cells to differentiate into spinal progenitor cells, and subsequently into motor neurons, through a pathway recapitulating that used in vivo.
Journal ArticleDOI
Distinct Roles for Secreted Semaphorin Signaling in Spinal Motor Axon Guidance
Andrea B. Huber,Artur Kania,Tracy S. Tran,Chenghua Gu,Natalia V. De Marco García,Ivo Lieberam,Dontais Johnson,Thomas M. Jessell,David D. Ginty,Alex L. Kolodkin +9 more
TL;DR: It is shown that motor axon growth and guidance are impaired in the absence of Sema3A-Npn-1 signaling, and that Sema2F-NPN-2 signaling guides the axons of a medial subset of LMC neurons to the ventral limb, but plays no major role in regulating their fasciculation.
Journal ArticleDOI
Conditional rhythmicity of ventral spinal interneurons defined by expression of the Hb9 homeodomain protein.
Jennifer M. Wilson,Robert Hartley,David J. Maxwell,Andrew J. Todd,Ivo Lieberam,Julia A. Kaltschmidt,Yutaka Yoshida,Thomas M. Jessell,Robert M. Brownstone +8 more
TL;DR: A novel population of glutamatergic interneurons located adjacent to the ventral commissure from cervical to midlumbar spinal cord levels are described, which suggest that they are candidate locomotor rhythm-generating interneuron networks.
Journal ArticleDOI
Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen.
Judith Alferink,Ivo Lieberam,Wolfgang Reindl,Andrea Behrens,Susanne Weiß,Norbert Hüser,Klaus Gerauer,Ralf Ross,Angelika B. Reske-Kunz,Parviz Ahmad-Nejad,Hermann Wagner,Irmgard Förster +11 more
TL;DR: It is shown that CCL17 expression in mice is found in activated Langerhans cells and mature DCs located in various lymphoid and nonlymphoid organs, and is up-regulated after stimulation with Toll-like receptor ligands, indicating that CCR17 production is a hallmark of local DC stimulation in peripheral organs but is absent from the spleen as a filter of blood-borne antigens.
Journal ArticleDOI
A Cxcl12-Cxcr4 Chemokine Signaling Pathway Defines the Initial Trajectory of Mammalian Motor Axons
TL;DR: It is shown that the chemokine receptor Cxcr4 is expressed on the axons of vMNs as they follow their ventral trajectory, whereas its ligand, Cxcl12, is expressed by mesenchymal cells surrounding the ventral neural tube.